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Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Liposomes could improve how skin care products work but are costly and not very stable.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Testosterone improves mood and thinking skills; finasteride has no effect.

Using neurohormones to control keratin can lead to new skin disease treatments.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Honokiol helps protect skin from damage and aging caused by cigarette smoke.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Dermatologists are the main innovators in noninvasive cosmetic procedures, with other specialties also contributing significantly.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.

A low-starch/low-dairy diet may help overweight women with PCOS lose weight and improve metabolism, but more research is needed.

AcSDKP may help prevent skin and hair aging and promote their growth.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

Aquaporins could be new drug targets for treating polycystic ovary syndrome.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.