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Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

New micelle solutions greatly improve skin delivery of certain antifungal drugs.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Methotrexate reduced the need for steroids in asthma patients without worsening their condition.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

Some common medications can harm male fertility, but many effects can be reversed.

Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.