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    Research 421–450 of 1000+

    1. The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention 2011 · 147 citations
    2. Age-associated inflammation inhibits epidermal stem cell function Genes & development · 2012 · 144 citations
    3. Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors Clinical Cancer Research · 2013 · 136 citations
    4. Characterization and Management of Hedgehog Pathway Inhibitor-Related Adverse Events in Patients With Advanced Basal Cell Carcinoma ˜The œoncologist · 2016 · 127 citations
    5. Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know? Reviews in Endocrine and Metabolic Disorders · 2015 · 111 citations
    6. Association of Suicidality and Depression With 5α-Reductase Inhibitors JAMA Internal Medicine · 2017 · 90 citations
    7. Immune-related alopecia (areata and universalis) in cancer patients receiving immune checkpoint inhibitors 2016 · 87 citations
    8. 5-Alpha Reductase Inhibitors and Erectile Dysfunction: The Connection The Journal of Sexual Medicine · 2008 · 78 citations
    9. The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression Korean Journal of Urology · 2014 · 75 citations
    10. Effects of 5-alpha reductase inhibitors on erectile function, sexual desire and ejaculation Expert Opinion on Drug Safety · 2012 · 71 citations
    11. New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence Journal of Investigative Dermatology · 2012 · 68 citations
    12. Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta) Teratology · 1997 · 67 citations
    13. Efficacy and safety of the oral Janus kinase inhibitor baricitinib in the treatment of adults with alopecia areata: Phase 2 results from a randomized controlled study Journal of The American Academy of Dermatology · 2021 · 66 citations
    14. Sexual dysfunction in subjects treated with inhibitors of 5α-reductase for benign prostatic hyperplasia: a comprehensive review and meta-analysis International Journal of Andrology · 2017 · 66 citations
    15. The efficacy and safety of 5α-reductase inhibitors in androgenetic alopecia: a network meta-analysis and benefit–risk assessment of finasteride and dutasteride Journal of Dermatological Treatment · 2013 · 66 citations
    16. Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation EMBO journal · 2003 · 65 citations
    17. The enzyme and inhibitors of 4-ene-3-oxosteroid 5α-oxidoreductase Steroids · 1995 · 64 citations
    18. Efficacy and safety of deuruxolitinib, an oral selective Janus kinase inhibitor, in adults with alopecia areata: Results from the Phase 3 randomized, controlled trial (THRIVE-AA1) Journal of the American Academy of Dermatology · 2024 · 63 citations
    19. Protein-phosphatase inhibitors block root hair growth and alter cortical cell shape of Arabidopsis roots Planta · 1994 · 61 citations
    20. A model for the turnover of dihydrotestosterone in the presence of the irreversible 5α-reductase inhibitors GI198745 and finasteride Clinical Pharmacology & Therapeutics · 1998 · 60 citations
    21. The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness. The Journal of Clinical Endocrinology and Metabolism · 1994 · 59 citations
    22. Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials The Journal of Sexual Medicine · 2016 · 57 citations
    23. Cutaneous effects of the most commonly used antidepressant medication, the selective serotonin reuptake inhibitors Journal of The American Academy of Dermatology · 2006 · 55 citations
    24. Enduring sexual dysfunction after treatment with antidepressants, 5α-reductase inhibitors and isotretinoin: 300 cases International journal of risk & safety in medicine · 2018 · 54 citations
    25. Persistent erectile dysfunction in men exposed to the 5α-reductase inhibitors, finasteride, or dutasteride PeerJ · 2017 · 50 citations
    26. Actions of 5α-reductase inhibitors on the epididymis Molecular and Cellular Endocrinology · 2006 · 48 citations
    27. 5 Alpha-reductase inhibitors: whatʼs new? Current opinion in urology · 2003 · 47 citations
    28. Novel Clove Essential Oil Nanoemulgel Tailored by Taguchi’s Model and Scaffold-Based Nanofibers: Phytopharmaceuticals with Promising Potential as Cyclooxygenase-2 Inhibitors in External Inflammation International Journal of Nanomedicine · 2020 · 45 citations
    29. Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 45 citations
    30. New 5?-reductase inhibitors: In vitro and in vivo effects Steroids · 2005 · 45 citations