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Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.

New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Medicinal herbs might treat hair loss by affecting genes and pathways related to lipid and glycerophospholipid metabolism.

Estrogen therapy can reduce skin aging but has cancer risks.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Targeting the Smoothened receptor shows promise for treating certain cancers.

The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.

Modern skin cancer treatments can cause skin side effects and hair loss, affecting patients' quality of life.

T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.

FGF21 can help reduce skin inflammation caused by C. acnes.

The exact causes of baldness are not fully understood, limiting treatment options.

Inhaling medicine may reduce side effects and improve treatment for a major lung cancer type.

Tadalafil and Finasteride may help treat aggressive melanoma.

Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.

Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Type I interferons play a key role in the development of various skin diseases.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Botanicals like green tea extract show potential for hair growth, but more research is needed.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Minoxidil and retinol together help hair grow.