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Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Lithium treatment can cause increased hair shedding and hair loss in patients.

The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.

Apremilast did not work for treating severe alopecia areata.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.

Minoxidil slows down skin cell growth and may help treat scars and skin conditions.

Scientists found new, better-working inhibitors for a hormone-related enzyme.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

The document concludes that certain chemicals can help maintain stem cell pluripotency and that understanding cell states is crucial for tissue regeneration.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.

A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

No definitive link between finasteride and male breast cancer, but further research is needed.

Tofacitinib can temporarily improve hair growth in alopecia universalis, but its effectiveness may decrease over time.

Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.

A medication may help with hair growth in psoriasis, and a skin condition might be linked to a specific bacteria.

Finasteride helps reduce heart enlargement in heart failure patients.

Finasteride's potential harms are hard to accurately measure.