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    Research 661–690 of 1000+

    1. Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice Journal of Investigative Dermatology · 2011 · 173 citations
    2. ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change Journal of experimental botany · 2013 · 161 citations
    3. The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention 2011 · 147 citations
    4. Effects of Finasteride (MK-906), a 5<i>α</i>-Reductase Inhibitor, on Circulating Androgens in Male Volunteers* The Journal of Clinical Endocrinology and Metabolism · 1990 · 147 citations
    5. Age-associated inflammation inhibits epidermal stem cell function Genes & development · 2012 · 144 citations
    6. Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors Clinical Cancer Research · 2013 · 136 citations
    7. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor Journal of the American Chemical Society · 1996 · 136 citations
    8. Characterization and Management of Hedgehog Pathway Inhibitor-Related Adverse Events in Patients With Advanced Basal Cell Carcinoma ˜The œoncologist · 2016 · 127 citations
    9. Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control Experimental Dermatology · 2005 · 127 citations
    10. Indications for a brain‐hair follicle axis: inhibition of keratinocyte proliferation and up‐regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P The FASEB Journal · 2001 · 125 citations
    11. Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production JAMA · 2012 · 124 citations
    12. Comparison of finasteride (proscar®), a 5α reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5α reductase inhibition The Prostate · 1993 · 124 citations
    13. External genitalia abnormalities in male rats exposed in utero to finasteride, a 5α-reductase inhibitor Teratology · 1990 · 122 citations
    14. Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know? Reviews in Endocrine and Metabolic Disorders · 2015 · 111 citations
    15. 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder Neuropsychopharmacology · 2015 · 110 citations
    16. The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer 2008 · 108 citations
    17. Androgen receptor–mediated inhibition of cutaneous wound healing 2002 · 108 citations
    18. Association of Suicidality and Depression With 5α-Reductase Inhibitors JAMA Internal Medicine · 2017 · 90 citations
    19. Immune-related alopecia (areata and universalis) in cancer patients receiving immune checkpoint inhibitors 2016 · 87 citations
    20. Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor Toxicology and Applied Pharmacology · 1993 · 86 citations
    21. 5-Alpha Reductase Inhibitors and Erectile Dysfunction: The Connection The Journal of Sexual Medicine · 2008 · 78 citations
    22. Chronic Restraint Stress Inhibits Hair Growth via Substance P Mediated by Reactive Oxygen Species in Mice PLoS ONE · 2013 · 76 citations
    23. Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition Journal of Molecular Medicine · 2005 · 76 citations
    24. The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression Korean Journal of Urology · 2014 · 75 citations
    25. Outcome of long-term treatment with the 5α-reductase inhibitor finasteride in idiopathic hirsutism: clinical and hormonal effects during a 1-year course of therapy and 1-year follow-up Fertility and Sterility · 1996 · 75 citations
    26. Post-tyrosinase Inhibition of Melanogenesis by Melatonin in Hair Follicles in Vitro Journal of Investigative Dermatology · 1980 · 75 citations
    27. The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen and Sexual Function in Healthy Young Men 2008 · 72 citations
    28. Effects of 5-alpha reductase inhibitors on erectile function, sexual desire and ejaculation Expert Opinion on Drug Safety · 2012 · 71 citations
    29. Keratinocyte Growth Inhibition through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells 2009 · 70 citations
    30. Clinical and endocrine effects of finasteride, a 5α-reductase inhibitor, in women with idiopathic hirsutism Fertility and Sterility · 1995 · 70 citations