48 citations
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May 2013 in “Canadian Medical Association Journal” This article discusses common causes of hair loss, specifically androgenetic alopecia and alopecia areata, but reports no new clinical findings.
9 citations
,
June 2024 in “Cell Reports” This study found that hair follicles play a significant role in regulating skin barrier function, with disruptions in the upper hair follicle affecting the epidermis, influencing processes like desquamation and sebum release, and leading to cell movement into the epidermis.
5 citations
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January 2015 in “Case reports in medicine” In this case report, a novel missense mutation c.1360G>C (p.Ala454Pro) in the MBTPS2 gene was identified in a boy with typical IFAP syndrome and severe atopic features, although no phenotype/genotype correlation was established.
3 citations
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January 2020 in “Clinical dermatology review” This review describes distinct trichoscopic findings for various alopecias in individuals with skin of color, but reports no new clinical results.
August 2025 in “American Journal of Dermatopathology” In this study, researchers presented cases of cellular neurothekeoma in three male family members with early-onset in infancy, suggesting a potential genetic component and inheritance pattern, which deviates from the typical presentation seen mostly in women between 20–30 years.
This study highlights that traumatic anserine folliculosis is a benign condition often seen in young males, which can be diagnosed without invasive biopsies using clinical examination and dermoscopy.
December 2024 in “Annals of Medicine and Surgery” Early diagnosis of pseudopelade of Brocq in men is crucial to prevent permanent hair loss.
December 2021 in “Journal of clinical images and medical case reports” This descriptive study observed that a "moth-eaten" pattern of hair loss can occur in several skin diseases, with lichen planopilaris and discoid lupus erythematosus being among the most common conditions identified in patients from Baghdad, emphasizing its potential as a diagnostic tool for clinicians.
28 citations
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February 2014 in “Journal of Cutaneous Pathology” In this study, researchers observed that keratoacanthoma exhibits dynamic follicular differentiation throughout its stages, with changes in specific keratin expressions, and regressed lesions showing epidermal rather than follicular characteristics.
18 citations
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March 2009 in “Experimental Dermatology” This study suggests that pilomatricoma can differentiate towards various hair follicle structures, including hair matrix, hair cortex, follicular infundibulum, outer root sheath, and hair bulge.
8 citations
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March 2017 in “Experimental Dermatology” In this exploratory study, researchers found slightly increased levels of inflammatory markers in scalp skin affected by androgenetic alopecia, suggesting differential gene expression involved in hair cycle and keratin production.
2 citations
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January 1989 in “The Nishinihon Journal of Dermatology” This study found that seborrheic keratosis lesions contain high levels of hair sheath keratin, suggesting they may originate from the upper hair follicle.
June 2026 in “Experimental Dermatology” This study used single-cell RNA sequencing to explore the cellular differences between small and large wound tissues during the hair follicle regeneration stage, revealing variations in keratinocyte subpopulations and extracellular matrix interactions associated with wound size.
April 2025 in “Veterinary Dermatology” This study observed that dermoscopy is a useful technique for distinguishing between infundibular keratinising acanthoma and follicular cysts in dogs, with specific dermoscopic features noted for each.
January 2024 in “Veterinary Dermatology” In this case report, proliferative, lymphocytic, infundibular mural folliculitis and dermatitis have been documented in a female Labrador retriever in a location outside North America for the first time, detailing the dog's clinical symptoms, histopathological findings, and treatment.
November 2022 in “Journal of Investigative Dermatology” This study observed that dandruff is linked to a weakened immunoprivilege in hair follicles, with reduced Langerhans cells and increased epidermal CD4+ and CD8+ T cell infiltration.
2 citations
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April 2019 in “Experimental Dermatology” This study observed that applying a pulling force to hair follicles led to significant compression of nuclei in certain cell layers and distinct collagen changes at different follicle depths.
25 citations
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June 2015 in “Clinical, Cosmetic and Investigational Dermatology” This study found that using an electrical microneedling device enhanced the penetration of liposomal melanin-fluorescein into hair structures and widened the follicular infundibulum in ex vivo human skin models.
1 citations
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April 2024 in “Journal of Cutaneous Pathology” This article presents a case of spontaneous, recurrent necrotizing infundibular crystalline folliculitis in the inguinal region and suggests unknown etiology possibly linked to microbiome and sebaceous gland dysfunction.
June 2023 in “Research Square (Research Square)” In this study, researchers used spatial transcriptome profiling to identify immune disturbances in the peri-infundibular region of androgenetic alopecia patients’ hair follicles, finding increased CD4+ T cells with a bias toward Th2 immune responses compared to controls.
20 citations
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April 2011 in “British Journal of Dermatology” Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.
11 citations
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June 2012 in “Acta histochemica” This study found that Gsdma3 mutations in mice led to thicker skin and longer hair infundibula, possibly by negatively regulating β-catenin expression in the epidermis.
June 2022 in “International Journal of Research -GRANTHAALAYAH” This article discusses the role of the hair follicle as a miniorgan involved in bioelectricity and energy transfer in living organisms, but it reports no new research findings.
This case report describes the dermoscopic features of two cases of the tumor of the follicular infundibulum, contributing new insights as they had not been previously detailed in the literature.
22 citations
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June 2013 in “Australasian Journal of Dermatology” Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.
12 citations
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May 2017 in “Journal of pharmaceutical and biomedical analysis” In this study, researchers developed a method using scalp cyanoacrylate biopsy and advanced imaging techniques to effectively measure and visualize the distribution of anti-dandruff shampoo ingredients zinc pyrithione and climbazole within the scalp follicular infundibulum.
46 citations
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September 2011 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that certain zinc pyrithione shampoos effectively deliver antifungal agents to the scalp's follicular infundibulum, correlating with reduced Malassezia populations, likely influenced by particle size optimizing such delivery.
January 2025 in “International Journal of Dermatology” This case report describes a patient with eruptive tumor of follicular infundibulum, emphasizing the need for dermatologists to include it in the differential diagnosis of acquired facial hypopigmentation.
62 citations
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September 2014 in “PLoS ONE” This study identified distinct human and bacterial protein profiles in sebaceous follicular casts, with acne samples showing proteins linked to inflammation and normal samples showing proteins involved in stress protection.
10 citations
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April 2013 in “Veterinary dermatology” In this study, four dogs with a novel skin disease showed clinical lesions involving verrucous, crusted papules and plaques, and responded variably to immunosuppressive therapy, suggesting an immune-mediated cause.