1 citations
,
January 2026 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this study, LC-OCT was used to distinguish between subtypes of scarring alopecia, laying the groundwork for further hypotheses and future research in larger and longitudinal studies to examine treatment responses.
69 citations
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December 2015 in “Journal of Controlled Release” This study found that nanocapsules formulated as a dispersion and applied with massage may enhance follicular uptake of clobetasol propionate while minimizing its skin penetration, offering a potential improvement over conventional treatments for scalp diseases.
1 citations
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January 2022 in “PLoS Pathogens” In this study, researchers developed a rapid platform using primary human lung tissues to identify SARS-CoV-2 targets and test antiviral compounds, achieving highly reproducible results across viral variants.
This article reviews a clinical case of pseudofolliculitis, highlighting its chronic nature, commonality in individuals with curly hair, and suggests management strategies, but reports no new clinical results.
April 2023 in “Journal of Investigative Dermatology” This research developed new in vitro models for high-throughput screening of drugs that could protect or restore immune privilege in hair follicles, finding that Tofacitinib was effective in preventing inflammation-related marker upregulation, while Tacrolimus and αMSH worked specifically in outer root sheath keratinocytes.
36 citations
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April 2019 in “Journal of Herbal Medicine” This review discusses the therapeutic potential of Ganoderma lucidum's secondary metabolites, noting their diverse health benefits, such as anticancer and antioxidant effects, without presenting new experimental results.
30 citations
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May 2019 in “Medicinal Research Reviews” This review discusses molecular and cellular strategies to improve muscle and skin regeneration and reduce scarring after cleft lip repair, offering potential benefits for function and aesthetics.
18 citations
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July 2001 in “International Journal of Dermatology” This case report documents a successful response to griseofulvin and prednisolone treatment in a 12-year-old boy with lichen planopilaris, characterized by patchy hair loss and distinct skin changes.
3 citations
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July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that K17−/− mice suffered more severe hair follicle damage but showed reduced epidermal inflammation after ionizing radiation, with K17's absence leading to aberrant cell cycle progression due to altered p53 genome binding and reduced B-Myb degradation.
3 citations
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April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study presents a new method using primary human lung tissue cells to rapidly identify viral entry factors and therapeutics for SARS-CoV-2, revealing compounds overlooked by conventional screening systems.
3 citations
,
January 2023 in “PloS one” In this study, hair-follicle-associated pluripotent stem cell implantation improved functional recovery and reduced inflammation in a mouse model of intracerebral hemorrhage.
2 citations
,
January 2024 in “Advances in Dermatology and Allergology” This study suggests a potential role for S100A7 and IL-17 in the pathogenesis of lichen planopilaris.
1 citations
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December 2022 in “Biomolecules & therapeutics” This study found that a long-term astrocyte culture model can effectively study astrocyte senescence and suggests minoxidil as a potential candidate to regulate brain aging by normalizing dysregulated gene expression in aged astrocytes.
February 2025 in “Skin Appendage Disorders” This review discusses the dermatologic side effects and potential therapeutic benefits of GLP-1 receptor agonists, such as facial fat loss and wound healing, emphasizing the need for further research.
This study found that blood cell count derived parameters were similar across non-cicatricial alopecia groups but showed general differences when compared to psoriasis and hidradenitis suppurativa. Among patients with alopecia areata, modulating platelet number and volume may serve as a therapeutic marker.
1 citations
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February 2024 in “Preprints.org” This review discusses the pharmacology and potential therapeutic effects of rare ginsenoside compound K on metabolic disorders but presents no new clinical results, highlighting the need for further studies on its bioavailability and toxicity.
178 citations
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December 2011 in “Journal of Dermatological Case Reports” This review discusses the application of trichoscopy in diagnosing various hair and scalp diseases and reports no new clinical results; the authors emphasize its role as a non-invasive diagnostic tool.
66 citations
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January 2017 in “Acta dermato-venereologica” This review suggests that isotretinoin's effects on severe acne and various cancers may result from apoptosis, which might also explain its adverse effects through genetic variability.
48 citations
,
January 2024 in “Immune Network” This review highlights recent insights into how IL-15 influences T cell responses and contributes to immunopathogenesis in various diseases, suggesting its crucial role in TCR-independent activation and potential in optimizing therapeutic strategies.
25 citations
,
November 2008 in “Ophthalmic Plastic and Reconstructive Surgery” This study found no significant differences in sensation recovery or scar formation between radiofrequency and scalpel incisions in upper blepharoplasty, although radiofrequency caused greater tissue damage.
21 citations
,
January 2015 in “Dental research journal” In this study, women with polycystic ovary syndrome were found to have a higher prevalence of periodontal diseases compared to healthy controls, possibly due to shared inflammatory mechanisms.
16 citations
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January 2018 in “International Journal of Trichology” In this study, minoxidil significantly downregulated interleukin-1 alpha expression in human keratinocyte cells, suggesting an anti-inflammatory effect that may be a mechanism of action in treating alopecia.
14 citations
,
August 2021 in “Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy” This research discusses the potential antitumor effects of metformin, a common diabetes medication, noting its controversial influence on different malignant tumors and its uncertain mechanisms. Understanding these effects on tumors may aid in the development of new cancer treatments.
14 citations
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July 2021 in “Bioinformatics” This study demonstrates the use of rPanglaoDB, an R package for combining public single-cell datasets, to create the first unbiased transcriptome profile of fibrocytes, revealing their role in tissue healing.
11 citations
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December 2020 in “Journal of Drugs in Dermatology” This study reported that COVID-19 skin manifestations, such as exanthema and chilblains, varied in timing but resolved positively with proper treatment.
10 citations
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May 2024 in “Lasers in Surgery and Medicine” This study found that laser hair removal effectively reduces disease severity in hidradenitis suppurativa with minimal side effects, likely due to the destruction of hair follicle units.
10 citations
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May 2020 in “Dermatologic therapy” In this study, a patient with recalcitrant lichen planopilaris and frontal fibrosing alopecia showed significant improvement after receiving four doses of the interleukin-23 monoclonal antibody tildrakizumab.
1 citations
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May 2022 in “Frontiers in Pharmacology” This study found that astilbin downregulates effector CD4+ T cell activities through the CYP1B1/ROS/PPARγ pathway, suggesting its potential use in treating inflammation.
1 citations
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October 2020 in “International Journal of Research in Dermatology” This study found that short vellus hair and yellow dots are common dermoscopic findings in alopecia areata, with variations indicating disease activity or remission.
1 citations
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July 2024 in “Journal of Associated Medical Sciences” This review highlights the mechanisms and therapeutic potential of mesenchymal stem cell-derived exosomes in regenerative medicine and discusses recent advances in their use for treating various ailments, without presenting new clinical findings.