January 2022 in “Journal of family medicine” This case report highlights the challenges of misdiagnosis in women with PCOS and emphasizes the importance of a holistic approach to address interconnected endocrine and reproductive dysfunctions.
2 citations
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March 2015 in “Expert opinion on orphan drugs” This review discusses recent advances in the treatment of alopecia areata, highlighting new potential therapies like JAK inhibitors and PRP, and reports no new clinical results.
22 citations
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September 2019 in “Trends in Immunology” This paper proposes that acne vulgaris is a transient inflammatory response during adolescence due to changes in facial skin's microbiota and sebum environment rather than a stable skin condition.
June 2026 in “Clinical and Experimental Dermatology” In this study, researchers observed a rare presentation of alopecia areata characterized by hair shafts with segmental heterochromia and changes in thickness, indicating a fluctuating low-level inflammatory process with recovery periods in the hair's normal characteristics.
November 2022 in “Journal of Investigative Dermatology” This study reported that an HS-associated NCSTN mutation in iPSC-derived skin organoids led to altered hair follicle stem cell differentiation and increased expression of proteins linked to HS inflammation.
April 2024 in “Journal of Pakistan Association of Dermatologists” This study found that secretome research in dermatology is growing and has potential for developing novel skin disorder therapies, with collaboration among countries enhancing advancements.
October 2023 in “Journal of the American Academy of Dermatology” This source reports that clascoterone cream has been approved in the U.S. for treating acne vulgaris in patients aged 12 and older, suggesting it works by competing with dihydrotestosterone at androgen receptors to mitigate acne's effects.
February 2026 in “Nature Communications” In this study, researchers created a detailed human skin cell atlas by analyzing over 700,000 cells, finding that disrupted communication among specific immune and stromal cell subsets may play a key role in initiating and sustaining chronic skin inflammation in atopic dermatitis.
4 citations
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January 2025 in “The Journal of Cell Biology” This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.
1 citations
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September 2017 in “Frontiers in Laboratory Medicine” This review discusses recent research on the relationship between gut microflora and depression, highlighting the potential for new insights into the pathogenesis and treatment of major depressive disorder.
January 2013 in “Cahiers Pedagogiques” This review examines how calorie restriction affects stem cell potency and tissue regeneration, indicating potential benefits for aging-related pathologies across various mammalian systems but presents no new findings.
306 citations
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April 2019 in “International Journal of Molecular Sciences” This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.
27 citations
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June 2017 in “Expert opinion on investigational drugs” This review discusses ongoing and past trials for novel acne treatments, focusing on topical agents with potential sebosuppressive, antimicrobial, or anti-inflammatory effects, without reporting new clinical results.
5 citations
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August 1976 in “Biochemical Society transactions” This review discusses the effects of steroids on the skin and does not report any new research findings.
4 citations
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August 2021 in “The Malaysian journal of medical sciences/The Malaysian Journal of Medical Science” This review discusses the impact of calorie restriction on enhancing stem cell potency and regenerative abilities in mammalian tissues and reports no new experimental results.
1 citations
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January 2010 in “Elsevier eBooks” Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
November 2025 in “ACS Nano” This study reported the development of a pH-responsive microreactor that effectively targets infections by eradicating over 99.9% of MRSA and reprogramming the immune response to promote healing, achieving complete infection clearance and tissue regeneration in a 7-day period.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers developed a hierarchically engineered microreactor that effectively combats infected wounds by releasing antimicrobials at acidic sites, eradicating MRSA while avoiding resistance, and enhancing tissue repair through immune system modulation.
January 2019 in “Springer eBooks” Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
January 2025 in “Journal of Drugs in Dermatology” This study highlights consensus statements from an expert panel, emphasizing the overlooked role of scalp barrier health in hair growth and dandruff, and notes that most prior research has focused on inflammatory diseases rather than dandruff.
January 2021 in “Springer eBooks” This chapter reviews skin manifestations in common rheumatic diseases, particularly those with polyarthritis, and offers a differential diagnosis of erythema nodosum without presenting new research findings.
July 2024 in “Journal of Investigative Dermatology” In this study of mouse models, researchers found that glutaminolysis is crucial for macrophages to switch from a pro-inflammatory to a pro-resolving state, aiding tissue repair by preventing prolonged inflammation and influencing gene expression.
4 citations
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September 2024 in “Skin Research and Technology” This study provides a comprehensive overview of the current state and emerging trends in SD (seborrheic dermatitis) research, aimed at aiding clinical practitioners and researchers in understanding valuable insights for decision-making and identifying future research directions.
January 2026 in “Journal of Dermatological Science” This study suggests that DcR3 can reprogram macrophages towards a reparative state, enhancing wound healing and hair follicle regeneration, making it a potential target for treating chronic wounds and alopecia.
1 citations
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December 2022 in “Parodontologiya” This study found that adding carboxytherapy to standard periodontal treatment significantly reduced inflammation and restored blood flow without causing adverse effects, indicating its high effectiveness as part of a comprehensive approach to treating inflammatory periodontal diseases.
5 citations
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October 2001 in “British Journal of Ophthalmology” This abstract describes the initial success of intralesional cidofovir for SCC treatment and states that it has not shown systemic toxicity, but it does not report new clinical trial results.
3 citations
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January 2021 in “Journal of Research in Medical Sciences” This review examines the interplay between metabolic syndrome and dermatologic conditions and reports no clinical results, emphasizing the need for awareness of their interconnected impacts when managing inflammatory skin diseases.
November 2025 in “The Journal of Immunology” This study identified specific genes upregulated in skin γδ T cells involved in alopecia areata, with findings suggesting these cells contribute to disease pathogenesis through inflammatory and Th1 response mechanisms in mouse and possibly human skin.
19 citations
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August 2018 in “JAMA dermatology” This study found that skin mesenchymal stem cells from hidradenitis suppurativa patients overexpress proinflammatory and anti-inflammatory cytokines, suggesting their potential contribution to the disease's pathogenesis.
This source reviews current understanding of fibroblast lineage differentiation and its role in wound healing, highlighting the potential to reprogram adult cells for scar-free repair by emulating fetal-like regenerative states.