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Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Certain mice without specific receptors or mast cells don't lose hair from stress.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Teriflunomide is safe and tolerable for treating relapsing-remitting multiple sclerosis, with manageable side effects.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Advanced human skin models improve drug development and could replace animal testing.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Wnt signaling is crucial for skin wound healing and reducing scars.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

RTA 408 cream protects mice from radiation skin damage.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.