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This retrospective cohort study found that individuals with alopecia totalis or universalis have a higher prevalence of systemic autoimmune diseases, particularly endocrine diseases and inflammatory bowel disease, compared to those with patchy alopecia areata.

In this study, researchers developed a near-infrared-responsive nanoplatform that synergistically enhances chronic wound healing by accelerating mitochondrial restoration and immune modulation, leading to enhanced wound repair and high-quality healing in diabetic rat models.

This abstract reviews recent findings on genetic factors in acne, highlighting the potential of genetic studies to advance understanding of its pathogenesis, but reports no new clinical results.

In this study, researchers developed a DNA/GelMA-based cryogel platform that uses phototherapy to combat MRSA infection and promote scarless wound healing, showing enhanced bactericidal activity, tissue regeneration, and anti-inflammatory effects in vivo, suggesting a promising approach for treating infected skin wounds.

Arg1+ macrophages may play a role in causing alopecia areata.

This study analyzed 24 Japanese cases of fibrosing alopecia in a pattern distribution and found a distinctive "parachute" hair loss pattern, emphasizing unique clinical characteristics potentially influenced by racial factors.

In this study, researchers did not find any genome-wide significant genetic signals linked to comorbid chronic inflammatory disorders in patients with alopecia areata, but exploratory analysis suggested potential associations worth further study.

This review discusses central centrifugal cicatricial alopecia, its similarities to lichen planopilaris, and emphasizes the need for further research due to its underdiagnosis and impact on African-descended women.

Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.

This review discusses the association between scarring alopecia and inflammatory processes in common acquired bullous disorders of the scalp, and reports no new clinical findings.

This study developed an all-natural hydrogel that promotes diabetic wound healing by converting pro-inflammatory M1 macrophages to anti-inflammatory M2 macrophages in a simple and biosafe manner.

In this study, researchers analyzed the clinical phenotype and primary pathogenic links in patients who survive the acute phase of a critical illness and rely on prolonged intensive care, finding that these patients show persistent inflammation, nutritional deficiencies, and other chronic complications over time.

This study found that soluble CD83 (sCD83) accelerated chronic and hard-to-heal wound healing and improved inflammatory and pro-resolving cytokine profiles, suggesting potential for therapeutic use.

This study using a genetic mouse model found that S. aureus-driven dysbiosis sustains inflammatory skin side effects from EGFR inhibitors, suggesting prophylactic antibiotic treatment may reduce rash severity without fixing barrier defects.

This study proposes a metal-organic gel-encapsulated microneedle system with antibacterial, anti-inflammatory, and pro-angiogenic properties for treating infected wounds, demonstrating potential for precise and adaptive management by targeting various stages of wound healing.

In this study, topical MR blockade improved delayed wound healing in glucocorticoid-pretreated mice by promoting anti-inflammatory macrophages and enhancing angiogenesis.

In this laboratory study, ASC-conditioned medium showed higher therapeutic potential than extracellular vesicles alone in reducing inflammation and catabolic activity in human chondrocytes with an osteoarthritis phenotype, highlighting its possible use in osteoarthritis management.

In this study, an immortalized MSC line from human adipose tissue showed potential for applications in regenerative medicine and inflammatory diseases through production of active factors, demonstrated in vitro.

In this study, the researchers reported that patient impacts and symptoms of hidradenitis suppurativa, as assessed by HSIA and HSSA measures, are associated with clinical characteristics such as the number of abscesses and inflammatory nodules.

This study found that an injectable calcium alginate-amelogenin hydrogel is biocompatible, degradable, anti-inflammatory, and promotes osteogenesis, which may enhance the bone healing process in jaw and facial bone defect areas by mediating the bone immune microenvironment.

This review synthesizes current evidence on therapies for dissecting cellulitis of the scalp, noting that biologics show promise for treatment-resistant cases, though systemic retinoids remain the first-line therapy.

This review explores recent advances in inflammation resolution and considers how macrophage reprogramming might help address severe COVID-19 outcomes, particularly those involving cytokine storms, but it reports no new experimental results.

This review discusses the role of macrophages in chronic wound healing and suggests that understanding their regulation can inform therapeutic approaches, but it reports no new results.

This article discusses how designing biomaterials to modulate immune responses has become a promising strategy for enhancing tissue repair and regeneration.

This study describes a rare form of congenital alopecia in domestic short hair cats, characterized by hair shaft defects and follicular dystrophy similar to those seen in certain mutant mouse strains.

This study found that a chitosan, chondroitin sulfate, and hyaluronic acid scaffold improved wound healing in rats by promoting immune-stromal interactions, reducing inflammation, and supporting tissue regeneration with ~91% wound closure by day 17 compared to ~63% in controls.

In this review, researchers detail how immunosenescence and chronic neuroinflammation contribute to Parkinson's disease progression, exploring potential therapeutic strategies targeting this axis, such as senolytic agents and immune rejuvenation, while highlighting associated challenges and future research needs.

This study highlights the crucial, multifaceted roles of fibroblasts in wound healing and various diseases, including their dysregulation in diabetic foot ulcers, underscoring the need for targeted therapies to address complications and morbidity from such chronic conditions.

This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.

This study found that super-enhancers play a crucial role in driving malignant progression in squamous cell carcinoma stem cells through a regulatory network involving ETS2 transcription factors, highlighting the potential link between high ETS2 levels and poor patient outcomes in head and neck cancers.