Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this review, the authors discuss various skin conditions linked to hyperandrogenism, such as acne and alopecia, with a focus on androgen-targeted therapies, suggesting these are generally more effective than non-androgen-targeted options.

This study used a mouse model to reveal that S100A4-positive cells, specifically fibroblasts and immune cells, play a crucial role in nipple development, essential for successful lactation, despite no issues with mammary morphology or milk production.

This study found that both genetic and epigenetic factors significantly influence age-related facial skin aging, with lifestyle and environmental factors also playing a substantial role.

This study reports that LED phototherapy is gaining popularity as a safe and effective non-invasive method for treating various skin conditions, enhancing skin rejuvenation, wound healing, and inflammation modulation, and is increasingly integrated into clinical protocols for conditions like acne vulgaris and signs of aging.

This study found that PT-LCG extends hair follicle activity and promotes continuous cashmere growth by enhancing lipid synthesis, remodeling the extracellular matrix, and modulating inflammatory signaling, offering insights into improving cashmere yield and quality through molecular breeding.

This study found that the systemic wrinkled skin phenotype in Xiang pigs involves gene expression changes and genetic variations associated with oxidative stress and extracellular matrix components, resembling features seen in Shar-Pei dogs.

This review synthesizes data suggesting that managing inflammation and oxidative stress may enhance the effectiveness of PRP therapy for hair regeneration, though standardizing PRP protocols remains challenging.

This study observed that topical application of palmitate or oleate accelerated the onset of the hair growth phase in mice, whereas glycolysis end product lactate delayed it, suggesting metabolic regulation as a promising approach for influencing hair growth.

According to this worldwide systematic review, psoriasis is a prevalent disease with adult prevalence ranging from 0.53% to 11.48%, more common in older populations and with substantial knowledge gaps in low and middle-income countries.

This study highlights a close link between metabolic syndrome, characterized by conditions like obesity and hypertension, and various inflammatory skin diseases, suggesting that mitochondrial dysfunction plays a key role in their pathogenesis and could be a target for new therapies.

This study identified 193 plasma proteins associated with prostate cancer risk, validating 20 high-risk proteins including KLK3, and pinpointed potential drug targets like HSPB1, RRM2B, and PSCA through genetic analysis, offering new insights for biomarkers and treatments.

This abstract highlights that alopecia treatment requires moving beyond outdated methods to a sophisticated approach that considers the complex interplay between genetic susceptibility and immune response in different types of hair loss. Results are not reported.

This study demonstrated that in mice, the absence of Jagged-1 expression in skin-resident regulatory T cells significantly delays wound healing by reducing the accumulation of neutrophils, highlighting the role of Jagged-1 in coordinating immune cell recruitment during injury.

This review examines the potential bidirectional relationship between polycystic ovary syndrome and periodontal diseases, but reports no new clinical findings; the authors suggest further research with larger sample sizes is needed to clarify the link.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

This article discusses the structure and function of sebaceous glands and their role in skin moisture but reports no new research findings.

In this study, researchers found that alopecia areata patients show a significant reduction in suppressive regulatory T-cells and an increase in inflammatory T-cell populations, suggesting an immunological imbalance contributing to the disease.

This study found that combining CelluTome system and RCM is a safe and effective protocol for evaluating wound healing responses in patients with epidermolysis bullosa.

In this study, the authors found that a botanical extract with anti-inflammatory and anti-oxidative properties stabilized hair loss and preserved natural hair pigmentation and strength over six months.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

This case report highlights the importance of considering SLE in young male patients with unexplained inflammatory musculoskeletal symptoms, as systemic inflammation was identified and symptoms improved with hydroxychloroquine.

This study highlights ongoing inequities in access and outcomes for inflammatory skin diseases in Latin America and emphasizes the need for regional registries, harmonized clinical guidelines, and policy reforms to improve equitable dermatologic care.

This study found that the protein C4BPA may link insulin resistance and acne vulgaris by influencing lipid metabolism and inflammatory pathways, suggesting it as a potential mediator in the pathogenesis of both conditions.

This study found that hirsutism in women is associated with elevated androgen hormone levels and increased serum TNFα, suggesting a link between androgen-driven inflammatory responses and excessive hair growth.

This study reports that an intervention decreased glucose and insulin levels, indicating improved insulin resistance, which is linked to a skin condition called acne vulgaris and other disorders associated with insulin resistance.

In this study, nonobese normotensive women with PCOS had higher left ventricular mass index compared to healthy controls, which was linked to inflammation and insulin resistance rather than androgen excess.

This review discusses the potential of ultraviolet (UV) radiation technologies in wound care, highlighting their antimicrobial properties and risks of DNA damage, but reports no new clinical findings.

This report discusses the various causes and clinical assessment of madarosis, emphasizing the importance of recognizing and diagnosing associated vision or life-threatening conditions, without presenting new findings.

This review explores new theories, diagnostic tools, and management strategies for primary cicatricial alopecia but reports no new clinical findings.