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This study found that androgen-regulated genes in hidradenitis suppurativa skin lesions are strongly linked to innate immunity pathways, indicating a potential connection between androgen signaling and inflammation in this condition.

This study found that 3D spheroid culture reprogrammed mesenchymal stem cells into a uniform immunosuppressive phenotype, suggesting potential therapeutic applications for inflammatory diseases like psoriasis.

In this study, researchers found that using bioinspired nanovesicles derived from inflammation memory-activated epidermal stem cells effectively promoted healing in diabetic wounds by reprogramming neutrophils to an anti-inflammatory phenotype in both laboratory and animal models.

This study highlights that ZNF750, a zinc-finger transcription factor, is crucial for epidermal differentiation and barrier formation in skin by activating genes involved in lipid processing and stratum corneum development, and links ZNF750 sequence variations to skin inflammatory diseases like psoriasis.

This pilot study suggests that skin-resident γδT-cells may play a significant role in the early stages of alopecia areata pathogenesis, indicating a potential new target for therapeutic management.

In this study, Mpzl3-/- mice developed severe seborrhea-like dermatitis with skin inflammation, indicating MPZL3's role in the skin condition's development, independent of adaptive immunity.

This study found that the immunological characterization of ichthyoses as psoriasiform or atopic patterns could help improve treatment, highlighting the need for targeted therapies to address itch and skin inflammation.

This study found that Wnt secretion is important for maintaining skin homeostasis in mice, as Evi-deficient mice developed psoriasis-like skin lesions and had an imbalance in immune cell populations.

This study found that specific TRPM5 modulators are unlikely to directly affect sebaceous glands, but safe TPPO analogues may provide moderate lipogenic and anti-inflammatory effects beneficial for dry skin conditions.

This study reports that folliculitis decalvans and lichen planopilaris phenotypic spectrum is an underdiagnosed form of cicatricial alopecia, potentially treatable with anti-inflammatory drugs used for lichen planopilaris.

The researchers reported that sulfated chitosan-containing sponges can modulate macrophage activity in diabetic wounds, reducing inflammation and promoting angiogenesis and tissue regeneration, which may enhance wound healing outcomes.

Aged skin heals slower due to more inflammation and disrupted cell communication.

This study found that a new autonomous, moisture-driven flexible electrogenerative dressing significantly accelerated chronic wound healing in a diabetic mouse model compared to the control group.

This article discusses the role of filaggrin gene mutations in understanding atopic dermatitis and their link to allergic sensitization but does not report new clinical results.

In this study, epidermal EGFR ablation in a mouse model led to significant local and systemic inflammatory responses, highlighting EGFR's role in maintaining skin immuno-homeostasis.

This study found that mice with a mutation in the Zdhhc13 gene exhibited increased susceptibility to skin cancer, highlighting a potential protective role of palmitoyl acyltransferase in skin carcinogenesis.

This review outlines current treatments for folliculitis decalvans and dissecting cellulitis of the scalp, noting conventional therapies' limitations and promising but limited results from targeted biologic agents.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

In this study, a biofunctional hydrogel incorporating mesenchymal stem cell-derived small extracellular vesicles promoted wound healing and reduced scar tissue formation by modulating the immune response in a mouse skin injury model.

Acne involves increased lipid production and inflammation, affecting skin cell behavior and treatment resistance.

This article reviews the complexities and challenges in hair transplant procedures, emphasizing the role of micro-inflammation and the usefulness of trichoscopy for detecting complications, and reports no new clinical results.

This study found that phenoxyethanol is the most common contact allergen in over-the-counter hair loss products, but its role in the development or exacerbation of frontal fibrosing alopecia remains unclear.

This paper discusses the potential roles of adipose tissue derived stem cells in skin regeneration and wound healing but emphasizes the need for further research on their effectiveness in clinical settings.

This study found that the DexIEME hydrogel promotes complete skin regeneration and scar attenuation in murine and porcine models, suggesting potential for treating deep dermal injuries.

Schwann cell and M2 macrophage interactions contribute to keloid growth by increasing matrix deposition.

Bioengineered skin models aging well, useful for studying aging and testing treatments.

In this study using diabetic rat models, the combination of AMD3100 and low-dose FK506 reduced wound healing time and improved microcirculation in diabetic foot ulcers, indicating a promising new systemic therapy.

This study examines the role of immune phenotypes and cytokines in the development of pathological scars, providing insights that may aid in early identification and treatment strategies for these scars.

This study suggests that targeting skin-infiltrated memory phenotype T cells could offer a new therapeutic approach to manage lymphopenia-related diseases like graft-versus-host disease and immune reconstitution inflammatory syndrome.

This study observes that TYK2 inhibition with BMS-986202 may extend hair follicle growth phases and decrease inflammatory cell markers in alopecia areata, suggesting potential for clinical application.