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    Glossary Inflammatory Phase

    body's initial response to injury involving immune system activation

    The Inflammatory Phase is the initial stage of the wound healing process, where the body's immune system responds to injury. During this phase, which typically lasts a few days, white blood cells, growth factors, and nutrients are sent to the wound site to fight infection, remove debris, and prepare for tissue repair. This phase is crucial for preventing infection and setting the stage for subsequent healing phases.

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    1. Pea Sprout Extract Promotes Hair Follicle Regeneration via Anagen Phase Prolongation and Dual Modulation of Oxidative and Inflammatory Signaling Journal of Microbiology and Biotechnology · 2025
    2. Local anti-inflammatory effect and immunomodulatory activity of chitosan-based dressing in skin wound healing: a systematic review Journal of clinical and translational research · 2022 · 4 citations
    3. A phase 2a trial of brepocitinib for cicatricial alopecia Journal of the American Academy of Dermatology · 2024 · 17 citations
    4. Effect of Free Long-Chain Fatty Acids on Anagen Induction: Metabolic or Inflammatory Aspect? International Journal of Molecular Sciences · 2025
    5. Gas chromatography coupled to mass spectrometry characterization, anti-inflammatory effect, wound-healing potential, and hair growth-promoting activity of Algerian Carthamus caeruleus L (Asteraceae) Indian Journal of Pharmacology · 2018 · 7 citations
    6. The inflammatory component of androgenetic alopecia Journal of The American Academy of Dermatology · 2021 · 3 citations
    7. A novel cell-penetrating peptide supports hair follicle growth through anti-inflammatory and growth factor–associated mechanisms in preclinical models BMC Biotechnology · 2026
    8. FC053 Pro-inflammatory cytokine cascade in human plucked hair 1997
    9. Sequential immunotherapy for alopecia areata: phase-driven immune rebalancing Expert Review of Clinical Immunology · 2025 · 1 citations
    10. Phase I-II trial of weekly bicalutamide in men with high PSA and negative biopsy Journal of Clinical Oncology · 2007 · 1 citations
    11. Anti-acne drugs in phase 1 and 2 clinical trials Expert opinion on investigational drugs · 2017 · 27 citations
    12. Evaluation of methotrexate-loaded surfactants, ceramides and cholesterol-based lamellar phases as a topical treatment for psoriasis Journal of Pharmacy and Pharmacology · 2022 · 2 citations
    13. Ultraviolet Radiation in Wound Care: Sterilization and Stimulation Advances in wound care · 2013 · 106 citations
    14. Nerve growth factor and burn wound healing: Update of molecular interactions with skin cells Burns · 2023 · 11 citations
    15. Laser therapy in superficial morphea lesions – indications, limitations and therapeutic alternatives Journal of Mind and Medical Sciences · 2020 · 10 citations
    16. 362 Not just a cell marker: DPP4 modulates regeneration of hair follicles in large wounds Journal of Investigative Dermatology · 2021
    17. Microagulhamento em couro cabeludo: um tratamento para a alopécia androgenética 2021
    18. Microneedling CRC Press eBooks · 2021
    19. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015 · 359 citations
    20. Comparison of Alopecia areata in Human and Nonhuman Mammalian Species Pathobiology · 1998 · 71 citations
    21. Histologic response to topically applied minoxidil in male-pattern alopecia Clinics in Dermatology · 1988 · 38 citations
    22. Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin Journal of Biological Chemistry · 2011 · 35 citations
    23. Mesenchymal Stromal Cell-Conditioned Medium for Skin Diseases: A Systematic Review Frontiers in Cell and Developmental Biology · 2021 · 26 citations
    24. Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression 2016 · 25 citations
    25. N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles Archives of dermatological research · 2015 · 13 citations
    26. Histologic Features of Alopecias–Part I: Nonscarring Alopecias Actas Dermo-Sifiliográficas · 2015 · 13 citations
    27. Hair regenerative effect of silk fibroin hydrogel with incorporation of FGF-2-liposome and its potential mechanism in mice with testosterone-induced alopecia areata Journal of Drug Delivery Science and Technology · 2018 · 12 citations
    28. Rice bran mineral extract increases the expression of anagen-related molecules in human dermal papilla through wnt/catenin pathway Food & Nutrition Research · 2017 · 9 citations
    29. A new strategy to modulate alopecia using a combination of two specific and unique ingredients. PubMed · 2013 · 7 citations
    30. Drug induced hair loss. The BMJ · 1989 · 4 citations