56 citations
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May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
24 citations
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May 2019 in “PLOS ONE” In this study, researchers observed that African spiny mice, Acomys cahirinus, are capable of regenerating skeletal muscle in dermal wound sites, unlike common mice, Mus musculus.
16 citations
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July 2012 in “Current pharmaceutical biotechnology” This review discusses the pathogenesis of common sebaceous gland diseases and their molecular pathways, but it reports no new clinical findings.
16 citations
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June 2018 in “JAAD case reports” This article reviews the differences in inflammatory processes between alopecia universalis and atopic dermatitis, focusing on type 1 and type 2 immune responses, but it reports no new results.
7 citations
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January 2021 in “Biology” This study documented a variety of skin lesions in COVID-19 patients, indicating that skin rashes might be an early or sole symptom of the disease.
3 citations
,
March 2019 in “Chinese Medical Journal” In this study using mice, fractional CO2 laser therapy promoted hair regrowth by inducing moderate inflammation, enhancing VEGF-mediated angiogenesis, and activating the Wnt10b signaling pathway.
3 citations
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August 2019 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma with microneedling for hair loss was mostly well tolerated, but some patients experienced mild side effects like scalp itching, transient hair shedding, and lymphadenopathy.
1 citations
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September 2017 in “Frontiers in Laboratory Medicine” This review discusses recent research on the relationship between gut microflora and depression, highlighting the potential for new insights into the pathogenesis and treatment of major depressive disorder.
November 2025 in “Skin Appendage Disorders” This review discusses the role of perifollicular fibrosis in androgenetic alopecia and suggests that targeting specific signaling pathways could improve treatment outcomes, but reports no new clinical results.
January 2025 in “Journal of Food Biochemistry” In this study, 2′‐Fucosyllactose (2′‐FL) administration significantly reduced hair loss and increased hair length and thickness in a testosterone-induced androgenic alopecia mouse model, suggesting potential as a therapeutic agent for AGA.
October 2024 in “The American Journal of Gastroenterology” This study described a case where both alopecia universalis and Crohn's ileitis in a 23-year-old man showed remarkable improvement with the JAK1 inhibitor upadacitinib, highlighting its potential as a treatment for patients with concurrent conditions.
August 2023 in “Medical Hypotheses” In this review, researchers discussed the anti-inflammatory and immunomodulatory properties of metformin and hypothesized that its topical application could benefit those with alopecia areata, given its effects on immune pathways, hair regrowth, and autoimmune disease management.
April 2023 in “Journal of Investigative Dermatology” This study explored COVID-related chilblains using transcriptomics and found they showed a distinct interferon and JAK/STAT pathway activation, absent in vaccine-related chilblains, with inflammatory cell types varying over time.
December 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This mini review discusses insights into the pathogenesis of hidradenitis suppurativa, highlighting genetic mutations, autoinflammation, and the effectiveness of biologics, and introduces the concept of autoinflammatory keratinization disease, without reporting new clinical results.
May 2020 in “International journal of dermatology and venereology” This study introduces the term "hair matrix cyst" for a cyst with both pilomatricoma and epidermal cyst characteristics, highlighting its potential for misdiagnosis among similar skin conditions.
In this study, exosomes were identified as influential in skin biology, demonstrating potential in accelerating wound healing by modulating inflammation and enhancing tissue regeneration, though their use remains primarily cosmetic pending FDA approval.
April 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that polygonum multiflorum may treat androgenic alopecia by mediating the PI3K/Akt pathway to regulate apoptosis, inhibit inflammation and oxidative stress, and induce melanin production.
70 citations
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June 2023 in “International Journal of Molecular Sciences” In this review, researchers explored how air pollutants increase oxidative stress and inflammation in human skin, affect vitamin D synthesis, and interact with the skin microbiota, also discussing AhR/Nrf2 as a potential target for treating pollution-related skin conditions.
3 citations
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September 2025 in “Frontiers in Immunology” This review discusses the complex role of immune disturbances and the JAK-STAT pathway in alopecia areata, noting the success of JAK inhibitors in treatment, while highlighting ongoing debates and challenges in targeting other pathways like IL-17 and TNF-α.
1 citations
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January 2025 in “Frontiers in Immunology” In this study, researchers found that cytokine dysregulation linked to genetic background is present in both patients and healthy but genetically related individuals in two autoimmune skin diseases, Pemphigus vulgaris and Alopecia areata, suggesting that protective immune mechanisms may prevent disease manifestation in predisposed individuals.
April 2026 in “Asian Journal of Research in Pharmaceutical Sciences” This review highlights the promising potential of Semecarpus anacardium Linn. in promoting hair growth due to its antioxidant and anti-inflammatory properties but emphasizes the need for further human clinical trials and safe formulation practices due to its associated toxicity in raw form.
February 2026 in “Eduvest - Journal Of Universal Studies” This review discusses the molecular mechanisms and therapeutic effectiveness of Janus Kinase Inhibitors for inflammatory skin diseases, suggesting these inhibitors have a rapid onset and favorable safety profile compared to conventional treatments.
December 2025 in “Frontiers in Veterinary Science” This study found that PT-LCG extends hair follicle activity and promotes continuous cashmere growth by enhancing lipid synthesis, remodeling the extracellular matrix, and modulating inflammatory signaling, offering insights into improving cashmere yield and quality through molecular breeding.
February 2024 in “Molecules/Molecules online/Molecules annual” In this study, NMN was found to reverse hair follicle atrophy, thinning, and sparsity in mice induced by DHT, and significantly decreased DHT-induced inflammation and oxidative stress in cultured human dermal papilla cells, enhancing hair growth-related markers.
22 citations
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November 2024 in “Bioactive Materials” This study found that 3D-printed polyamine-modified hydrogels facilitate M2 macrophage polarization and exosome secretion, enhancing skin cell compatibility and promoting wound healing and hair follicle induction in an animal model through specific signaling pathways, suggesting potential for skin disorder therapies.
53 citations
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July 2002 in “Journal of Investigative Dermatology” The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.
263 citations
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February 2020 in “International journal of molecular sciences” This paper discusses the potential roles of adipose tissue derived stem cells in skin regeneration and wound healing but emphasizes the need for further research on their effectiveness in clinical settings.
20 citations
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December 2020 in “Actas Dermo-Sifiliográficas” This review examines the JAK/STAT signaling pathway's significance in inflammatory skin diseases and evaluates the efficacy and safety of oral and topical JAK inhibitors for treating vitiligo and alopecia areata. Results are not reported in this study.
11 citations
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August 2023 in “Burns” This review explores the molecular mechanisms through which NGF may enhance burn wound healing by reducing healing time and improving scar quality, but it presents no new clinical results.
9 citations
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May 2023 in “Stem Cell Research & Therapy” This study found that mesenchymal stem cell treatment alleviated atopic dermatitis-like symptoms in a mouse model by modulating immune and inflammatory responses, with gene expression changes suggesting pathways for potential personalized treatment approaches.