69 citations
,
December 2006 in “Archives of dermatology” This entry contains no research abstract, so no scientific findings or conclusions are reported.
45 citations
,
November 2015 in “Dermatologic Clinics” This review discusses the potential hormonal and metabolic factors influencing hidradenitis suppurativa and highlights the need for further research to explore hormonal dysregulation's role in the disease.
36 citations
,
June 2015 in “International journal of toxicology” This study established a new mouse model for TCE-induced skin sensitization and reported that proinflammatory cytokines TNF-α, IFN-γ, and IL-2 significantly contribute to this sensitization process.
28 citations
,
August 2018 in “Dermatologic Surgery” This abstract is a listing of affiliations and funding, with no new study or results reported.
27 citations
,
December 2015 in “Mayo Clinic Proceedings” This review presents an evidence-based algorithm for managing hidradenitis suppurativa in primary care, highlighting the need for more research on treatment effectiveness and the disease's pathogenesis.
26 citations
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April 2019 in “Advances in wound care” This study found that tannic acid accelerated wound healing in rats by modulating inflammatory cytokines, increasing growth factors, and activating the Erk 1/2 pathway.
25 citations
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July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that applying topical imiquimod during mid and late telogen in mice activates hair follicle stem cells and influences immune cell infiltration, promoting hair cycle entry independently of Wnt signaling.
24 citations
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March 2022 in “Journal of the American Academy of Dermatology” Adalimumab improved folliculitis decalvans in most patients.
24 citations
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May 2019 in “PLOS ONE” In this study, researchers observed that African spiny mice, Acomys cahirinus, are capable of regenerating skeletal muscle in dermal wound sites, unlike common mice, Mus musculus.
17 citations
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August 2019 in “Frontiers in Immunology” This review examines non-invasive methods for diagnosing inflammatory skin diseases like lupus erythematosus and psoriatic inflammation using samples from plucked hair and skin tape-strips, but no new clinical results are presented.
13 citations
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July 2015 in “Archives of dermatological research” This study found that the spermidine analog N1-methylspermidine prolonged hair follicle growth and decreased inflammation and oxidative stress in cultured hair follicles, suggesting potential relevance for treating inflammatory scalp diseases.
12 citations
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September 2018 in “Journal of Drug Delivery Science and Technology” This study found that a new hydrogel formulation of basic fibroblast growth factor showed promise in promoting hair regrowth and reducing inflammation in testosterone-treated mice.
9 citations
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September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” This study found that reducing testosterone levels in male mice accelerates wound healing and decreases inflammation, suggesting a potential therapeutic target for improving wound repair in elderly males.
8 citations
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January 2014 in “Journal of Stem Cell Research & Therapy” This review discusses advancements in stem cell therapy for cutaneous radiation syndrome, highlighting the potential of various stem cell sources to improve wound healing and reduce symptoms, but reports no new clinical results.
7 citations
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January 2022 in “Scientific Reports” This study found that Acanthus ebracteatus extract and verbascoside induced dermal papilla cell proliferation and reduced inflammatory cytokine release in vitro, suggesting potential for anti-hair loss applications.
7 citations
,
April 2019 in “Aesthetic Surgery Journal” This study found that repeated applications of both nonactivated and activated PRP in rats led to increased hypersensitivity to pain, which may be linked to elevated nerve growth factor levels and inflammatory mediators.
5 citations
,
March 2025 in “Pediatric Dermatology” This study found that alopecia areata is linked to genetic factors, specifically HLA haplotypes on chromosome 6, and involves immune privilege collapse at hair follicles which is mediated by the JAK-STAT pathway and pro-inflammatory cytokines like IFN-γ.
4 citations
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August 2023 in “Materials” This review highlights that synthetic biodegradable polymers like PVA, PCL, PLA, PLGA, PU, and PEO/PEG can address the limitations of natural polymers in wound healing, offering improved mechanical properties and slower degradation, thereby enhancing their application as wound dressings.
This review examines cepharanthine's antiviral potential against COVID-19 and finds no clinical results yet; it highlights cepharanthine as a potent inhibitor of coronavirus in preclinical models.
3 citations
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September 2025 in “Frontiers in Immunology” This review discusses the complex role of immune disturbances and the JAK-STAT pathway in alopecia areata, noting the success of JAK inhibitors in treatment, while highlighting ongoing debates and challenges in targeting other pathways like IL-17 and TNF-α.
2 citations
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April 2010 in “Cancer Research” In this study, epidermal EGFR ablation in a mouse model led to significant local and systemic inflammatory responses, highlighting EGFR's role in maintaining skin immuno-homeostasis.
1 citations
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February 2022 in “Experimental Dermatology” This study found that the secretory profiles of adipose-derived stem cells vary between balding and non-balding scalp areas in androgenetic alopecia patients, suggesting involvement of angiogenic and inflammatory processes in the condition's development.
1 citations
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January 2014 in “Springer eBooks” Adult acne is more common in women, often linked to hormones, and can be harder to treat.
1 citations
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June 2006 in “Experimental dermatology” This article reviews possible pathogenesis scenarios for hidradenitis suppurativa and emphasizes the need for focused research on the innate immune system of hair follicles to better understand the disease.
This review outlines current treatments for folliculitis decalvans and dissecting cellulitis of the scalp, noting conventional therapies' limitations and promising but limited results from targeted biologic agents.
April 2026 in “Frontiers in Immunology” In this study, researchers did not find any genome-wide significant genetic signals linked to comorbid chronic inflammatory disorders in patients with alopecia areata, but exploratory analysis suggested potential associations worth further study.
April 2026 in “International Journal of Clinical Oncology” This review found that adding immune checkpoint inhibitors to cancer treatment regimens likely increases the incidence of specific drug-related skin toxicities in adult Asian patients, highlighting the need for careful monitoring and management strategies.
March 2026 in “Journal of obstetrics and gynaecology research” In this study, Ark-e-Kasni was found to alleviate PCOS symptoms in rats by restoring hormonal levels, improving insulin sensitivity, and reducing inflammation and cystic follicles, suggesting its therapeutic potential via diverse molecular mechanisms.
November 2024 in “NeoReviews” This case report details an extremely low-birth-weight preterm neonate presenting with unique dermatologic symptoms, leading to a diagnosis of neonatal inflammatory skin and bowel disease due to a novel homozygous EGFR gene mutation, highlighting the importance of genetic testing in ambiguous cases.
December 2017 in “Journal of Cosmetic Dermatology” This article does not contain an abstract, so it provides no new research findings or clinical results.