69 citations
,
January 2020 in “Veterinary World” This review examines factors influencing dermatophyte infection in companion animals, focusing on prevalence, clinical signs, pathogenesis, immune response, and the impact of cortisol and cytokines, but reports no new clinical results.
15 citations
,
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identifies KLK14 as a significant factor contributing to hair defects and skin inflammation in a mouse model of Netherton syndrome.
13 citations
,
August 1991 in “The Journal of the American Osteopathic Association” This research found evidence of inflammatory involvement in androgenetic alopecia, with higher deposition of certain immune components in the scalp of affected patients compared to those without baldness.
6 citations
,
December 2022 in “International Journal of Molecular Sciences” This review explores the hormonal factors related to hidradenitis suppurativa, emphasizing insulin resistance and pro-inflammatory adipokines, but reports no new clinical findings and suggests further research is needed.
1 citations
,
September 2013 in “Elsevier eBooks” This review discusses factors affecting hair aging, such as inflammation and UV exposure, and examines potential anti-aging benefits of antioxidants and nutraceuticals for hair, but reports no new clinical results.
1 citations
,
May 2012 in “Hair transplant forum international” This article reviews the genetic and androgenic factors influencing the development of androgenetic alopecia and reports no new findings; the authors highlight a need for further research into the underlying mechanisms.
2 citations
,
June 2025 in “Biomolecules” This review highlights that gut dysbiosis and bacterial extracellular vesicles are key factors in PCOS pathophysiology, and suggests AI-driven analysis of these profiles could enhance diagnostic accuracy and treatment personalization, though ethical concerns like data privacy and bias must be considered.
119 citations
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January 2012 in “Nutrition & Metabolism” This article suggests that modern lifestyle changes, including diet, stress, and chronic anti-inflammatory medication use, may disrupt the natural process of inflammation resolution, increasing vulnerability to chronic disease.
16 citations
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July 2020 in “International Journal of Molecular Sciences” This study found that ruxolitinib modulated inflammatory changes and stimulated growth factor signals by blocking the JAK-STAT pathway in an in vitro model of alopecia areata.
12 citations
,
January 2005 in “Journal of Cosmetic Dermatology” This review discusses the natural progression of androgenetic alopecia and potential factors influencing its long-term prognosis, reporting no new clinical results.
1 citations
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April 2022 in “Global health & medicine” This review explores long COVID symptoms in Japan and discusses potential contributing factors, highlighting persistent SARS-CoV-2 infection's role, but reports no new clinical results; it also considers vaccination as a treatment option.
October 2005 in “CRC Press eBooks” Telogen effluvium is a condition where hair falls out due to various factors like illness, stress, or nutrient deficiency.
271 citations
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May 2019 in “Cells” This review discusses the therapeutic potential of MSC-derived secretomes for treating degenerative and inflammatory diseases, reporting no new clinical results but highlighting their proposed mechanisms and advantages over direct MSC transplantation.
15 citations
,
May 1999 in “Journal of Investigative Dermatology” Alopecia areata is complex, with genetic and immune factors, and animal models are key for future treatment research.
3 citations
,
October 2024 in “International Journal of Molecular Sciences” This study found that non-activated platelet-rich plasma from acetylsalicylic acid-treated patients increased inflammatory cytokines, affecting platelet activation and possibly influencing outcomes in PRP therapies.
2 citations
,
May 2000 in “Additives for Polymers” This review discusses the role of primary and secondary factors in androgenetic alopecia, suggesting that plant-based folk remedies may ameliorate these factors when used alongside conventional therapies; it reports no new clinical results.
This review highlights that iron deficiency is a significant yet often overlooked contributor to the development of immune-mediated inflammatory skin diseases, suggesting that iron dysregulation may drive inflammation and metabolic imbalances in conditions like psoriasis and atopic dermatitis.
July 2024 in “Journal of Investigative Dermatology” Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.
October 2021 in “The Egyptian Journal of Hospital Medicine” In this study, intralesional platelet-rich plasma was found to be a beneficial and safe treatment option for oral lichen planus, an inflammatory disease affecting the oral mucosa.
2 citations
,
July 2024 in “Skin Research and Technology” Copper may protect against alopecia areata, while certain inflammatory markers increase risk.
April 2025 in “International Journal of Clinical & Medical Case Studies” This source explains that unlike genetic hormonal alopecia, alopecia areata is associated with inflammatory factors and may also involve psychological and genetic contributions.
4 citations
,
July 1994 in “Clinics in Dermatology” This review discusses the emergence and impact of eosinophilia-myalgia syndrome related to L-tryptophan and offers insights into environmental factors affecting sclerodermatous conditions, with no new research findings presented.
3 citations
,
June 2023 in “Nano today” This study reported that bioinks containing calcium molybdate nanoparticles and dermal papilla cells can promote hair regrowth in vivo by creating an anti-inflammatory environment and activating the mTOR signaling pathway in macrophages.
December 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that IL-1β may play a role in inflammatory signaling pathways in papulopustular rosacea, contributing to its pathogenesis.
January 2019 in “Springer eBooks” Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.
September 2023 in “JEADV Clinical Practice” This study reviewed existing literature and found that androgenic alopecia may be associated with cardiovascular risk factors, while evidence for alopecia areata and cicatricial alopecias is limited and sometimes contradictory.
48 citations
,
September 2017 in “Frontiers in Bioscience” This review explores the role of nanotechnology in wound healing, highlighting its potential through antimicrobial properties, selective inflammatory action, angiogenesis promotion, and its use in drug and gene delivery.
1 citations
,
February 2020 in “Cureus” This review examines the complex relationship between polycystic ovary syndrome and its associated skin conditions, highlighting an intricate network influenced by hormonal, genetic, and inflammatory factors but reports no new clinical results.
89 citations
,
March 1996 in “Proceedings of the National Academy of Sciences” This study found that homozygous mutant mice with a hypomorphic CD18 mutation developed a chronic inflammatory skin disease resembling human psoriasis, potentially implicating additional genetic factors in disease susceptibility.
87 citations
,
March 2017 in “Journal of Clinical Investigation” In this study, researchers identified PSENEN mutations that can lead to a form of Dowling-Degos disease, characterized by follicular hyperkeratosis and an increased susceptibility to acne inversa, especially in the presence of certain trigger factors.