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Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

The cancer drugs bortezomib and lenalidomide cause skin side effects in many patients.

COVID-19 may harm male fertility and damage the reproductive system.

Use PRP and ASC-BT for hair loss and wound healing, but more research needed.

Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.

Canine epidermal neural crest stem cells could be a promising treatment for spinal cord injuries in dogs.

An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

FDA-cleared devices may help treat hair loss, but more research needed; consult dermatologist before use.

Local injections of nanosized rhEPO can speed up skin healing and improve quality after deep second-degree burns.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.

Men with hair loss have higher BMI, waist size, blood pressure, and are linked to smoking and inactivity.

Many adults in Porto have acne, but few know or treat it.

The document concludes that diagnosing and treating hair loss is complex and requires understanding its psychological effects and underlying causes, while also calling for more research and new treatments.

Alternative treatments show promise for hair growth beyond traditional methods.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Certain factors like allergies, nail problems, and hair loss patterns can predict how well someone with patchy hair loss will respond to skin cream treatments.

The article suggests using safety measures and telemedicine for aesthetic dermatology during COVID-19, while some procedures can still be done safely.

The document concludes that products like PRP and PRF show promise for tissue healing, but evidence of their effectiveness is inconsistent.

Permanent hair dye mixtures can irritate and damage the skin.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

Smad2/3-dependent TGF-β signaling increases during wound healing.