165 citations,
September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
75 citations,
March 2009 in “Journal of The American Academy of Dermatology” CCCA is a hair loss type affecting African women, possibly caused by grooming and chemicals, with various treatments and needing more research.
33 citations,
April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
4 citations,
June 2002 in “Clinical and experimental dermatology” Effective treatment for hidradenitis suppurativa varies, with antibiotics commonly used and surgery as an option, but no single method is universally successful.
April 2024 in “Military Medical Research/Military medical research” Cellular and immunotherapies show promise for healing chronic wounds but need more research.
May 2023 in “Current Medicinal Chemistry” Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
April 2021 in “Journal of Investigative Dermatology” People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.
1 citations,
January 2024 in “Pharmaceuticals” A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.
1 citations,
October 2022 The conclusion suggests that managing antioxidant levels and the calcium to magnesium ratio may help address Long Covid and related chronic fatigue conditions.
19 citations,
September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
March 2014 in “Pediatric Clinics of North America” The document discusses how to identify and manage common skin conditions in children.
29 citations,
March 2019 in “British Journal of Dermatology” Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
5 citations,
February 2024 in “Frontiers in bioengineering and biotechnology” Electrospun scaffolds can improve healing in diabetic wounds.
5 citations,
May 2019 in “Archives of Dermatological Research” Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.
July 2018 in “British Journal of Dermatology” Mindfulness reduces anxiety and depression in skin disease patients; dermatologists and psychiatrists often lack confidence in treating psychodermatological conditions.
223 citations,
September 2018 in “Rheumatology” JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
46 citations,
April 2008 in “Archives of Dermatological Research” Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
23 citations,
April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.
14 citations,
April 2014 in “Medical Clinics of North America” The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.
2 citations,
January 2019 The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.
1 citations,
March 2024 in “Signal transduction and targeted therapy” NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
610 citations,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
291 citations,
January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
165 citations,
January 2014 in “Dermatology Research and Practice” Zinc is effective for treating various skin conditions, including warts and acne.
150 citations,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
79 citations,
October 2015 in “Journal of Dermatological Treatment” Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.
48 citations,
July 2018 in “Journal of The American Academy of Dermatology” Spironolactone helps reduce pain and lesions in hidradenitis suppurativa patients, and lower doses are also effective.
42 citations,
April 2021 in “Journal of clinical pharmacology” Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
39 citations,
June 2019 in “Toxins” Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.
32 citations,
December 2018 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.