Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review introduces the pilocutaneous syndrome of menopause, a set of skin and hair changes linked to estrogen decline, and discusses its recognition, diagnosis, and management without reporting new clinical results.

Immune system changes may contribute to female pattern hair loss.

This study identified shared gene expression changes and immune cell infiltration patterns that may contribute to hair loss in alopecia areata and cutaneous lupus erythematosus, but also highlighted factors that might preserve hair in psoriasis patients.

This article suggests that modern lifestyle changes, including diet, stress, and chronic anti-inflammatory medication use, may disrupt the natural process of inflammation resolution, increasing vulnerability to chronic disease.

This study suggests that diffuse alopecia areata initially involves an intense inflammatory attack during the anagen phase, progressing through different hair cycle stages with specific shedding patterns.

In a mouse model, this study found that exposure to PM2.5 leads to significant postpartum hair loss, apparent via morphological changes and elevated markers of inflammation, apoptosis, and fibrosis, potentially exacerbated by changes in hormone receptors and stem cell populations.

T cells affect skin cell genes in inflammatory diseases, and therapy can normalize these changes.

This review explores the potential impact of nutrition on immune-mediated inflammatory skin diseases and evaluates whether dietary changes could help in treatment planning, but it presents no new clinical outcomes.

In this study, researchers observed that alterations in scalp microbiota might be linked to inflammation associated with alopecia areata, but it's unclear if these microbiota changes cause or result from hair loss, necessitating further investigation into their causal relationship and mechanisms.

In this study, researchers observed that dandruff involves altered keratinocyte activity and a low-grade inflammatory response characterized by increased interleukin-17-producing T-cells and CCL17 levels, but without significant changes in immune cell populations or skin barrier lipids.

This article reviews nail involvement in various skin diseases, such as psoriasis and lichen planus, and highlights characteristic changes but reports no new clinical findings.

This review highlights the crucial role of histone modification in the pathogenesis and treatment of chronic inflammatory skin diseases, and explores therapeutic strategies targeting these epigenetic changes to improve management of conditions such as psoriasis and atopic dermatitis.

In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.

This review discusses polycystic ovary syndrome, its detection, and treatments, concluding that lifestyle changes may offer sustainable management, although it reports no new clinical results.

Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.

In this study, researchers observed distinct aging signatures in mouse keratinocytes, with increased expression in older mice, and noted relevant pathway changes that were also evident in human skin, suggesting potential insights into intrinsic skin aging.

This study found that disrupting Lm332 expression in mice changes keratinocyte genetic expression, alters cell shape, and disrupts epidermal homeostasis, despite some compensatory anchorage by hair follicle basal cells.

This study found that dogs with dermatitis exhibited specific histological skin changes, such as hyperkeratosis and inflammatory cell infiltration, and showed increased leukocyte counts compared to non-dermatitis dogs.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

This paper proposes that acne vulgaris is a transient inflammatory response during adolescence due to changes in facial skin's microbiota and sebum environment rather than a stable skin condition.

This review investigates the potential benefits of cinnamon supplementation alongside lifestyle changes for managing obesity and polycystic ovary syndrome, but it reports no new clinical results.

This review discusses the cutaneous side effects of targeted anticancer therapies, such as rashes and hair changes, but presents no new clinical results.

Tocilizumab treatment was associated with significant hair regrowth in one patient and temporary hair loss followed by regrowth in another.

This study observed a high prevalence of postadolescent acne in adult women, which was often inflammatory and moderately severe, with persistent acne in half the cases and frequent involvement of the mandible.

This editorial synthesizes research on UV-induced skin damage, highlighting potential therapeutic strategies by mapping cellular changes, identifying molecular mechanisms, demonstrating melanocyte protection, and proving combination therapy effectiveness in conditions like vitiligo.

In this study, D-OCT imaging revealed distinct structural and vascular changes in patients with frontal fibrosing alopecia, highlighting the technique's potential for diagnosing and monitoring the condition's activity.

This review discusses the pilocutaneous syndrome of menopause, associated with skin and hair changes due to estrogen decline, and highlights an unmet need for recognition and targeted treatment.

This study found that an acne complex animal model using rabbits showed more pronounced clinical symptoms and measured changes compared to the traditional Kligman model.

This study found that mesenchymal stem cell treatment alleviated atopic dermatitis-like symptoms in a mouse model by modulating immune and inflammatory responses, with gene expression changes suggesting pathways for potential personalized treatment approaches.

This case report describes the first documented instance of idiopathic seasonal alopecia in a horse in Brazil, characterized by symmetrical hair loss and subsequent regrowth linked to seasonal changes.