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This study discusses the epithelial-immune microenvironment in chronic skin diseases, such as psoriasis and atopic dermatitis, and highlights current and future treatment strategies targeting inflammatory loops within these diseases.

This study found that TPA induces apoptosis in pig renal epithelial cells by affecting cell cycle proteins, and activated ras can prevent this process.

In this animal study, AGO (agomelatine) effectively alleviated testosterone-induced benign prostatic hyperplasia in rats by reducing oxidative stress and inflammation, indicating its potential as a therapeutic option for managing BPH through specific signaling pathways.

This study found that diffuse alopecia in HIV-1-infected patients is characterized by higher rates of follicular stem cell apoptosis compared to controls, suggesting a hair cycle disturbance associated with the infection.

This review discusses the antiviral potential of cepharanthine against SARS-CoV-2, noting its effectiveness in preclinical models but presenting no new clinical results.

This study suggests that Cepharanthine, a monomer in traditional Chinese medicine, may help treat COVID-19 by affecting multiple signaling pathways, and that TNF and IL-17 inhibitors used in rheumatoid arthritis, ankylosing spondylitis, and gouty arthritis might also be beneficial.

In this study, bovine milk-derived oligosaccharides were found to increase sebocyte proliferation, lipid content, and inflammatory mediator synthesis through the mTORC1 pathway, potentially contributing to milk-based inflammation in sebocytes.

In this study, women with PCOS who took 12 mg of Astaxanthin daily for 8 weeks showed a reduction in certain inflammatory markers and apoptosis-related genes, suggesting potential benefits for managing PCOS, though effects on symptoms like BMI and hirsutism were not significant.

This study identifies KLK14 as a significant factor contributing to hair defects and skin inflammation in a mouse model of Netherton syndrome.

This study found that NLRP1 in human melanoma cells promotes tumor growth by enhancing inflammasome activation and suppressing caspase-3 activity.

This study investigated the role of NLRP3 inflammasomes in alopecia areata and found that outer root sheath cells may contribute to inflammation by increasing IL-1β and HMGB1 secretion when stimulated with double-stranded RNA.

Plant-based treatments may help reduce BPH symptoms, but more research is needed.

This review discusses findings from genetic studies on acne, highlighting progress in understanding its molecular pathogenesis without reporting new clinical results.

This study found that sex hormones, specifically non-aromatizable androgens like DHT and A/T, significantly increase inflammatory cytokine expression in human adipocytes when stimulated by LPS.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

This study suggests that STAT3 signaling in keratinocytes is crucial for maintaining skin homeostasis by regulating hair follicle-specific keratin genes, potentially impacting dermatitis development through microbe-triggered inflammatory responses.

This study found that IL-1α promotes hair follicle regeneration and stem cell activation in an age-dependent manner by modulating inflammatory cells and oxidative stress in mice.

In this study, researchers found that sesamin, a component of sesamum, modulated the AR-MAPK-Wnt signaling pathway in DHT-stimulated HaCaT keratinocytes, demonstrating potential multi-target activity against molecular events in androgenetic alopecia.

This article discusses the historical and current uses of grape seeds in various industries but reports no new research findings.

This study reports that finasteride treatment in men with androgenetic alopecia appears to restore caspase and XIAP expression in hair follicles to levels similar to those in individuals without the condition.

Caspase-7 has functions in skin and hair that are not related to cell death.

This study reports that a plant extract from Orobanche rapum can stimulate skin rejuvenation and protect cutaneous microbiota, potentially creating healthier skin.

This study found that the small molecule honokiol may protect against inflammation, collagen breakdown, and cell damage caused by cigarette smoke in skin cells cultured in vitro.

In this study, naringenin and its methylated derivatives reduced depression-like behaviors and inflammation markers in mice exposed to finasteride, suggesting their potential as effective and safe anti-depressive agents.

This study found that 3D spheroid culture reprogrammed mesenchymal stem cells into a uniform immunosuppressive phenotype, suggesting potential therapeutic applications for inflammatory diseases like psoriasis.

This article reviews the role of perifollicular regulatory T cells in maintaining hair follicle integrity in the context of hidradenitis suppurativa and calls attention to inflammatory mechanisms without reporting new clinical results.

In this study, researchers found that using a 5-α reductase inhibitor may reduce inflammation-related cytokines associated with T-helper cell 1 and T-helper cell 2 in prostate tissues after surgery, but it did not affect those related to Th17 cells.

This study found that Acanthus ebracteatus extract and verbascoside induced dermal papilla cell proliferation and reduced inflammatory cytokine release in vitro, suggesting potential for anti-hair loss applications.

Baricitinib reduces inflammation and mitochondrial damage in skin cells.