6 citations
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January 2020 in “International journal of biological sciences” In this study, deletion of ROBO4 in mice ameliorated hair loss caused by elevated PAF levels, suggesting potential interplay with VLDLR-related pathways.
5 citations
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September 2021 in “Journal of cosmetic dermatology” This study found that alopecia areata patients had significantly abnormal T3, T4, TPOAbs, ANA, and lower vitamin D levels compared to healthy controls.
4 citations
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September 2024 in “Jurnal Pengolahan Hasil Perikanan Indonesia” In this study, researchers reported that compounds from Bruguiera gymnorhiza leaves showed anti-inflammatory potential in in silico analyses, with favorable drug properties and specific binding to the IKKβ receptor, suggesting possible development into anti-inflammatory drugs.
4 citations
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August 2024 in “Cells” This research found that certain inflammasome proteins, like caspase-1, ASC, IL-18, and IL-1β, were elevated in patients with aneurysmal subarachnoid hemorrhage (aSAH) compared to controls and suggested these proteins could serve as reliable biomarkers for inflammation, potentially predicting worse outcomes.
4 citations
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January 2023 in “Skin health and disease” This study shows that in a mouse model of Alopecia Areata, selective JAK1 inhibition facilitated hair regrowth and inflammation resolution while potentially offering a better safety profile compared to pan-JAK inhibition.
3 citations
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September 2024 in “Journal of Microbiology and Biotechnology” This study found that human placenta hydrolysate effectively inhibited atopic dermatitis development in stimulated human cells and a mouse model, suggesting its potential as a therapeutic agent for related skin diseases.
3 citations
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June 2024 in “Immunopharmacology and Immunotoxicology” This study found that cardamonin can reduce inflammation in TNF-α-stimulated human periodontal ligament cells by suppressing specific cytokines and chemokines and inhibiting key inflammatory signaling pathways.
2 citations
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July 2025 in “Journal of Health Population and Nutrition” This study suggests that managing sleep disorders, particularly those involving difficulty initiating sleep, may benefit from dietary interventions that reduce proinflammatory nutrients and increase anti-inflammatory nutrients.
2 citations
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June 2025 in “International Journal of Molecular Sciences” In this study, Carthamus caeruleus root juice exhibited in vitro anti-inflammatory effects by stabilizing human erythrocyte membranes and inhibiting albumin denaturation, as well as showing potential inhibition of COX-2 through in silico analysis; however, further research is needed to confirm efficacy and mechanisms.
2 citations
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September 2024 in “Journal of intelligent medicine.” This review consolidates various rational design strategies for nanozymes, emphasizing the mechanisms needed for precise design and exploring their applications in treating inflammatory diseases, diagnosing diseases, and environmental uses, while also discussing the challenges and future prospects in this emerging field.
2 citations
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June 2023 in “Research in Pharmaceutical Sciences” Bhamrung-Lohit may help with inflammation and oxidation.
2 citations
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March 2022 in “Journal of Personalized Medicine” Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.
1 citations
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February 2025 in “Journal of the Neurological Sciences” This study suggests that BTP levels in cerebrospinal fluid might help diagnose CIDP and predict therapy response but require validation in larger cohorts.
1 citations
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April 2023 in “International Journal of Molecular Sciences” This study found that Botryococcus terribilis ethanol extract significantly reduced inflammation markers in LPS-stimulated RAW264 cells, potentially via Axl inhibition and alteration of immune-related gene expression.
1 citations
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January 2017 in “Japanese Journal of Oral & Maxillofacial Surgery” In this case study, a woman with secondary syphilis showed significant improvement following treatment with benzyl penicillin potassium, as evidenced by a 3.7-fold decrease in rapid plasma reagin levels.
March 2026 in “Frontiers in Medicine” This study reviews advances in targeted therapies for moderate-severe dermatological conditions like plaque psoriasis and atopic dermatitis, reporting on newly approved treatments and highlighting the need for further innovations in managing rare inflammatory skin diseases through emerging laboratory techniques and trials.
This study found that Dex-loaded hyaluronic acid hydrogel microneedles significantly reduced pain in an acute inflammatory visceral pain model without sedation, suggesting a promising and patient-friendly alternative to intravenous delivery.
August 2025 in “International Journal of Molecular Sciences” This study found that compounds isolated from Osmanthus fragrans var. aurantiacus demonstrated antioxidative and anti-inflammatory activities, potentially offering therapeutic benefits for inflammatory bowel diseases by inhibiting COX-2 and iNOS enzymes and blocking ERK 1/2 MAPK signaling.
July 2025 in “International Journal of Biological Macromolecules” Fucoidan may help regrow hair and reduce inflammation in hair loss.
July 2025 in “Journal of Investigative Dermatology” Monocyte-derived dendritic cells play a key role in UVB-induced skin sensitivity and inflammation.
July 2025 in “Clinical Cosmetic and Investigational Dermatology” This study examines the role of immune phenotypes and cytokines in the development of pathological scars, providing insights that may aid in early identification and treatment strategies for these scars.
This study explored new molecular structures as potential COVID-19 treatments, identifying a compound called Hit15 that inhibited viral infection in lab settings and reduced inflammation markers in human neutrophils, suggesting further development is warranted.
July 2024 in “Journal of Investigative Dermatology” Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.
January 2024 in “Frontiers in immunology” This review highlights the crucial role of histone modification in the pathogenesis and treatment of chronic inflammatory skin diseases, and explores therapeutic strategies targeting these epigenetic changes to improve management of conditions such as psoriasis and atopic dermatitis.
April 2023 in “Dermatology practical & conceptual” This study observed that a tacrolimus solution (0.1%) applied to the scalp was effective and well-tolerated for treating inflammatory scalp conditions, with 72.7% of patients showing an excellent response after 2 months of treatment, which persisted after 6 months.
April 2019 in “Journal of Investigative Dermatology” This study observed that simvastatin promoted hair regrowth in a mouse model of alopecia areata by reducing inflammatory markers and T cell proliferation, partly through disruption of isoprenoid metabolite production.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
92 citations
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July 2001 in “The FASEB Journal” In this study, transgenic mice overexpressing the glucocorticoid receptor in certain epithelia showed skin development abnormalities resembling ectodermal dysplasia and exhibited reduced inflammatory responses.
1 citations
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January 2012 in “Hair therapy & transplantation” This review discusses hair loss treatments with natural compounds, noting their good safety profile but highlighting insufficient peer-reviewed data to support their effectiveness.
January 2024 in “Journal der Deutschen Dermatologischen Gesellschaft” This research paper reviews the mechanisms and management of non-biologic immunosuppressive drugs used in dermatology, highlighting their safety profiles and handling during pregnancy, breastfeeding, and vaccination, but does not report specific results on these aspects.