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    Glossary Inflammation

    body's natural response to injury or infection

    Inflammation is the body's natural response to injury or infection, characterized by redness, heat, swelling, and pain. It involves the activation of the immune system to eliminate harmful stimuli and initiate healing. While acute inflammation is a protective mechanism, chronic inflammation can lead to various health issues, including autoimmune diseases and tissue damage.

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    1. Mechanisms regulating skin immunity and inflammation Nature Reviews Immunology · 2014 · 610 citations
    2. Mechanisms and applications of the anti-inflammatory effects of photobiomodulation AIMS biophysics · 2017 · 520 citations
    3. Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture Cell · 2018 · 249 citations
    4. Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia Blood · 2010 · 245 citations
    5. Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization Cell Metabolism · 2014 · 222 citations
    6. Macrophages and fibroblasts during inflammation and tissue repair in models of organ regeneration Regeneration · 2017 · 201 citations
    7. Stress Inhibits Hair Growth in Mice by Induction of Premature Catagen Development and Deleterious Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways American Journal of Pathology · 2003 · 194 citations
    8. Linking diet to acne metabolomics, inflammation, and comedogenesis: an update Clinical, Cosmetic and Investigational Dermatology · 2015 · 138 citations
    9. Overexpression of protein kinase C-α in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-α expression but not tumor promotion Journal of Cell Science · 1999 · 135 citations
    10. Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease Stem Cell Research & Therapy · 2020 · 118 citations
    11. Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists Pharmacology & therapeutics · 2010 · 105 citations
    12. Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity Mediators of Inflammation · 2010 · 102 citations
    13. Maternal PPARγ protects nursing neonates by suppressing the production of inflammatory milk Genes & Development · 2007 · 102 citations
    14. Hyaluronidase Modulates Inflammatory Response and Accelerates the Cutaneous Wound Healing PLoS ONE · 2014 · 98 citations
    15. Thou shall not heal: Overcoming the non-healing behaviour of diabetic foot ulcers by engineering the inflammatory microenvironment Advanced Drug Delivery Reviews · 2023 · 90 citations
    16. miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of Keratinocytes Journal of Investigative Dermatology · 2020 · 90 citations
    17. Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation Stem Cell Research & Therapy · 2020 · 90 citations
    18. Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases Frontiers in immunology · 2019 · 88 citations
    19. Homing of stem cells to sites of inflammatory brain injury after intracerebral and intravenous administration: a longitudinal imaging study Stem Cell Research & Therapy · 2010 · 87 citations
    20. Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes Journal of Investigative Dermatology · 2017 · 77 citations
    21. Short-Chain Fatty Acids from <i>Cutibacterium acnes</i> Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes 2019 · 70 citations
    22. Effects of finasteride in patients with inflammatory chronic pelvic pain syndrome: a double-blind, placebo-controlled, pilot study Urology · 1999 · 65 citations
    23. Male sex hormones, aging, and inflammation Biogerontology · 2023 · 60 citations
    24. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice Journal of Immunology · 2015 · 59 citations
    25. Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy Cell death and differentiation · 2015 · 56 citations
    26. Ligand-Dependent Actions of the Vitamin D Receptor Are Required for Activation of TGF-β Signaling during the Inflammatory Response to Cutaneous Injury Endocrinology · 2012 · 56 citations
    27. Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells Cells · 2019 · 51 citations
    28. Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model Frontiers in Immunology · 2020 · 48 citations
    29. Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity Genes & Development · 2012 · 47 citations
    30. Roles of tumor suppressors in regulating tumor-associated inflammation Cell Death & Differentiation · 2014 · 44 citations