Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the expanding understanding of TRPV3's role in pain and skin pathology, while highlighting the need for further pharmacological research to fully resolve its functions.

Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.

This review discusses the roles that mesenchymal stem cells may play in reepithelialization of wounds, but reports no new clinical results.

This study observed that MAA beads improved vascularization in non-diabetic male mice by modulating the Shh signaling pathway in wound granulation tissue, but showed no such effects in females.

This study suggests that thermal imaging may aid in diagnosing cellulitis, potentially improving patient care, although its applicability to certain cases requires further investigation.

This study found that electrical epilation in organ-cultured human scalp skin perturbs hair follicles by causing inflammation, impairing melanin production, and possibly inhibiting post-epilation hair re-growth.

This study found that the peptide derivative beta-Ala-Pro-Dab-NHbenzyl may reduce wrinkles and sebum production in human skin by inhibiting dipeptidyl peptidase 4, suggesting potential for acne and skin inflammation treatment.

This study suggests that the mTOR signaling pathway may play a role in the pathophysiology of radiation dermatitis, with expression patterns of S6K1 protein differing from those in normal and inflamed skin.

In this study, researchers demonstrated that the Id2 gene acts as a direct target and effector of BMP signaling, playing a key role in maintaining quiescence in hair follicle stem cells in vivo.

In this study, researchers observed that African spiny mice, Acomys cahirinus, are capable of regenerating skeletal muscle in dermal wound sites, unlike common mice, Mus musculus.

This review discusses recent advancements in nanotechnology for treating hypertrophic scarring and atopic dermatitis, highlighting the potential of nanotherapeutic platforms in enhancing therapeutic effects by modulating the skin's microenvironment.

This study found that acne lesion formation involves early hyperkeratinization and inflammation around hair follicles, creating a self-sustaining cycle that may progressively worsen acne.

This review explores how adult skin epithelia preserve stem cell populations for hair follicle regeneration and wound healing, but reports no new experimental results.

This review discusses the composition, activation, and regulation of the JAK/STAT pathway and highlights its role and inhibitors in various diseases, but reports no new experimental results.

This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.

This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.

This review explores fibroblast heterogeneity in the mammalian dermis and suggests potential therapeutic applications by targeting fibroblast subtypes, but reports no new experimental results.

This review discusses the links between particulate matter exposure and skin diseases, highlighting oxidative stress and inflammation as key mechanisms; it reports no new clinical results.

This article reviews the role of stromal stem cells in mammalian wound repair, suggesting they may perform functions similar to blastemal cells in simpler organisms, but reports no new experimental results.

This review discusses the role of the TOR pathway in aging and suggests that rapamycin could potentially target age-related diseases, but reports no new clinical results.

This review discusses the limitations of animal models, particularly mice, in accurately predicting human skin wound healing outcomes and emphasizes understanding species-specific differences in skin characteristics for better translation to clinical settings.

This review examines clinical data on the efficacy and safety of JAK inhibitors used for immune-mediated conditions beyond rheumatoid arthritis, highlighting their potential therapeutic roles in various inflammatory diseases.

In this study, researchers found that mitochondrial complex I plays a crucial role in regulating innate immunity and bone remodeling, with Ndufs4 deletion causing systemic inflammation and osteopetrosis through various metabolic shifts and cellular mechanisms.

This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.

This article discusses the coordinated roles of different epidermal stem cells and other cell types in the skin's wound healing process and reports no new experimental results.

This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.

This study observed that applying JAK-STAT pathway inhibitors to mouse and human skin led to rapid hair growth by inducing the anagen phase of hair follicles.

This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.

This study found that mouse skin CD4(+) memory T cells are in equilibrium with the circulation under steady state but increase in specific clusters in response to infection or inflammation.

This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.