16 citations
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January 2018 in “Dermatology Online Journal” This review discusses platelet-rich plasma treatment for androgenic alopecia, summarizing current understanding of the disease and the need for standardized clinical trials, but it reports no new results.
11 citations
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December 2024 in “Stem Cell Research & Therapy” In this study, hUCMSCs-Exo significantly accelerated wound healing in rat perianal fistulas with notable safety, potentially through the activation of the HIF-1α/TGF-β/Smad signaling pathway.
10 citations
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January 1985 in “Elsevier eBooks” Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
7 citations
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November 2022 in “Biochemical and Biophysical Research Communications” This study investigated the heterogeneity of CD34+ cells in wound healing, identifying distinct cell clusters and suggesting potential therapeutic approaches for anagen and diabetic wounds.
7 citations
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March 2022 in “International Journal of Molecular Sciences” This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.
6 citations
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September 2024 in “Journal of Clinical Medicine” This review explored the relationship between autoimmune thyroiditis and various autoimmune skin conditions, highlighting shared genetic markers and immunological mechanisms, such as disrupted immune tolerance and oxidative stress, which may contribute to the development of these disorders.
5 citations
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May 2022 in “Biomedicines” This study found that the green alga Botryococcus terribilis and its novel compounds significantly promoted hair growth marker gene expression in hair follicle dermal papilla cells without cytotoxic effects.
4 citations
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June 2023 in “Frontiers in Aging” This scoping review evaluates the connection between hypoxia and declining sex hormonal signaling in middle-aged individuals, proposing a "middle-aging hypovascularity hypoxia hypothesis" as a potential mechanism influencing age-related diseases, with implications for developing strategies to maintain healthspan.
3 citations
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May 2021 in “Dermatologic Clinics” This article reviews potential therapeutic targets and comorbidities associated with male androgenetic alopecia, but reports no new clinical results; further study is needed for comprehensive management.
3 citations
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January 2017 in “Chinese Science Bulletin (Chinese Version)” This review discusses the gut-brain-skin axis and its role in skin diseases, advocating for treatments that integrate gut microbiota, mental health, and dietary interventions, but reports no new clinical results.
2 citations
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June 2022 in “Cells” The study found that growing dermal papilla cells in 3D spheroids enhances their activity with hair growth-promoting agents, such as minoxidil and TCQA, compared to traditional 2D cultures.
1 citations
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June 2024 in “Preprints.org” This review explores the roles of dermal sheath cells in wound healing, highlighting their multifunctional contributions to inflammation, proliferation, and extracellular matrix remodeling, and proposes new insights into tissue regeneration and repair, especially in differentiating between hairy and non-hairy skin sites.
September 2026 in “International Journal of Innovative Technologies in Social Science” This review discusses the relationship between physical activity and skin aging, highlighting that regular moderate exercise may benefit skin health but excessive exercise could increase oxidative stress and damage.
August 2026 in “British Journal of Dermatology” sCD83 shows promise for treating hair loss by promoting growth and reducing inflammation.
August 2026 in “Clinical Cosmetic and Investigational Dermatology” This study found that Hydroxypinacolone Retinoate (HPR) may alleviate UV-induced skin photoaging by enhancing collagen synthesis, reducing degradation, and modulating inflammatory and oxidative responses in a dose-dependent manner.
July 2026 in “Journal of Applied Pharmaceutical Research” This literature review indicates that skin aging involves complex interactions of both internal and external factors, leading to oxidative stress and cellular damage. The authors report promising results from novel anti-aging interventions, including antioxidants, senolytics, and herbal preparations, for slowing skin aging progression.
June 2026 in “Journal of Investigative Dermatology” This study found that certain proteins linked to immune suppression and melanogenesis are associated with repigmentation in vitiligo patients undergoing standard treatment, suggesting these proteins and their pathways play roles distinct from merely reversing skin lesions.
March 2026 in “International Journal of Dermatology” In this study, researchers observed that patients with androgenetic alopecia show differences in scalp microbial communities compared to the general population, including an increase in Cutibacterium acnes, particularly in males, which may interact with lipid and immune pathways to contribute to hair follicle miniaturization.
In this narrative review, researchers synthesized current evidence on topical metformin's potential benefits for various skin conditions, citing primarily preclinical studies that highlight its anti-inflammatory, antioxidant, and regenerative properties, although clinical translation requires further rigorous trials.
March 2026 in “Journal of Nanobiotechnology” This study developed a hydrogel microneedle system combining ginseng-derived exosomes and biomimetic nanoparticles to address oxidative stress, inflammation, and melanocyte deficiency in vitiligo, showing significant repigmentation in mice within 3 weeks by enhancing melanocyte protection and keratinocyte proliferation.
January 2026 in “Experimental Dermatology” This review discusses the role of keratinocytes in hidradenitis suppurativa, highlighting their genetic and metabolic influences on disease progression without presenting new clinical results.
November 2025 in “Skin Appendage Disorders” This review discusses the role of perifollicular fibrosis in androgenetic alopecia and suggests that targeting specific signaling pathways could improve treatment outcomes, but reports no new clinical results.
September 2025 in “Global Journal of Pharmacy & Pharmaceutical Sciences” This review analyzes PDRN's molecular mechanisms and therapeutic applications in anti-aging dermatology but reports no new clinical results, highlighting the need for more standardized protocols and long-term evaluations.
August 2025 in “Acta Biomaterialia” This study presents a novel hydrogel scaffold made from tilapia collagen, which when activated by ultrasound, reprograms macrophages to promote wound healing, enhance angiogenesis, and stimulate hair follicle regeneration, offering a potential new method for treating inflammatory wounds.
March 2025 in “MAEDICA – a Journal of Clinical Medicine” This review explores the potential impact of SARS-CoV-2 on benign prostatic hyperplasia and related lower urinary tract symptoms but reports no new clinical results, emphasizing the need for further studies to quantify these changes.
March 2025 in “Advanced Science” In this study, bioengineered hair germ microspheres made from HME hydrogels promoted hair follicle regeneration in vivo, suggesting a promising approach for hair loss treatment.
September 2024 in “JAMA Dermatology” In this case series, low-dose oral metformin was associated with improvements in symptoms and gene expression changes in Black female patients with treatment-resistant central centrifugal cicatricial alopecia, suggesting a potential therapeutic role for metformin in managing this condition.
June 2024 in “Journal of Allergy and Clinical Immunology” In this study, thymic stromal lymphopoietin (TSLP) induced IL-4/IL-13 from T cells, prompting sebum secretion and adipose loss, suggesting IL-4/IL-13 may affect skin barrier function in atopic dermatitis.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, Mpzl3-/- mice developed severe seborrhea-like dermatitis with skin inflammation, indicating MPZL3's role in the skin condition's development, independent of adaptive immunity.
January 2016 in “mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich)” This thesis presents a new scientific approach using specific models to gain insights into psoriasis and eczema, highlighting a molecular classifier that improves diagnostic accuracy and predicts therapeutic response for these conditions.