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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

The document concludes that more research is needed to fully understand the causes of PCOS.

The document concludes that diagnosing PCOS requires a thorough approach, considering various symptoms and risks, and calls for improved methods to identify PCOS types and prevent diabetes.

Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Frontal Fibrosing Alopecia is a poorly understood condition that is hard to treat and causes distressing hair loss.

Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.

The conclusion is that managing cholesterol is important for women, especially during pregnancy, breastfeeding, and with PCOS, and involves regular screening and careful treatment choices.

Skin aging reflects overall body aging and can indicate internal health conditions.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Lifestyle changes like diet and exercise are key for treating overweight women with polycystic ovary syndrome.

Most hair loss in children is caused by a few common conditions and is easy to diagnose, but rare types require careful evaluation.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

A man lost all his hair as a rare side effect after hepatitis C treatment.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.