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Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Lactate production is important for activating hair growth stem cells.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Sulforaphane from broccoli can help protect skin from sun damage.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Blocking JAK-STAT signaling can lead to hair growth.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

AXR3 and SHY2 genes control the growth and timing of root hair development in plants.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Male pattern baldness involves genetics, hormones, and needs better treatments.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Stem cell self-renewal is complex and needs more research for full understanding.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.