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Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.

Significant progress was made in understanding PXE, but effective treatments are still needed.

Inherited color dilution in rabbits is linked to DNA methylation changes.

Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.

Combining PRP with minoxidil significantly improves hair growth in AGA patients.

Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Mice can regrow hair on wounds due to specific cell interactions and mechanical forces not seen in rats.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Hair follicle stem cells can become nerve cells using specific treatments.

Stem cells show promise for nerve injury treatment, but more research is needed before human use.

Chrysanthemum zawadskii extract helps hair grow by stimulating hair cells.

ALRN-6924 may prevent hair loss caused by chemotherapy.

Freezing and storing special stem cells from hair follicles keeps their ability to grow hair and turn into different cell types.

TCDD disrupts skin stem cells, causing skin issues like chloracne.

Fat-derived stem cells and their secretions show promise for treating skin aging and hair loss.

Rat whisker cells can help turn other cells into nerve cells and might be used to treat brain injuries or diseases.

Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.

Substances from dental stem cells might help treat hair loss.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Hair follicle cells resist turning into skin cells.

Neural crest-derived progenitor cells in the cornea could help treat corneal issues without transplants.

Transplanted whisker follicles caused hair growth on the spine of mice.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

The new method can create hair follicle-like structures but not complete hair with roots and shafts, needing more improvement.

Old hair follicles grew better when moved to a young environment.