1 citations
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February 2022 in “Research journal of pharmacy and technology” This study suggests that Wrightia tinctoria extract, particularly its components Quercetin and Indirubin, may play a role in promoting hair growth when tested on albino male Wistar rats.
13 citations
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March 2021 in “British Journal of Pharmacology” This study found that KY19382 can effectively promote hair regeneration and follicle neogenesis in mice and human hair models by activating Wnt/β-catenin signalling, suggesting potential use for alopecia treatment.
471 citations
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October 2012 in “Cellular and Molecular Life Sciences” This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.
103 citations
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November 2014 in “Journal of Cell Biology” This study found that overexpression of miR-214 in keratinocytes inhibits hair follicle development and cycling by targeting β-catenin in the Wnt signaling pathway.
27 citations
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February 2014 in “Planta Medica” This study found that Scutellaria baicalensis extract and its main component baicalin inhibited androgen activation signaling and promoted proliferation of human dermal papilla cells, suggesting potential use in treating androgen-associated disorders.
19 citations
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August 2023 in “Experimental & Molecular Medicine” This study found that the CXXC5 protein is overexpressed in diabetic foot ulcer tissues, suppressing wound healing, and that the small molecule KY19334 accelerated healing in diabetic mice by activating the Wnt/β-catenin pathway.
18 citations
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July 2021 in “Molecular Medicine Reports” This review summarizes existing knowledge of how the WNT signaling pathway affects mesenchymal stem cells under various conditions, highlighting challenges and mechanisms for clinical applications.
4 citations
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January 2019 in “Elsevier eBooks” This review examines the current landscape of drug repositioning, highlighting that computational methods expand possibilities for reusing existing drugs to treat unmet medical needs. The authors discuss both the potential of these methods and the challenges faced in identifying new therapeutic applications.
3 citations
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August 2021 in “Cutis” This review examines CAM approaches for atopic dermatitis, psoriasis, and alopecia areata, providing dermatologists with current insights but includes no new clinical findings.
3 citations
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June 2021 in “Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512)” This review highlights phytochemicals, particularly flavonoids and phenolics, as potential supportive treatments for SARS-CoV-2 by interfering with viral proteins and providing anti-inflammatory effects; it suggests a foundation for future therapeutic and vaccine development efforts.
1 citations
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December 2021 in “Annals of phytomedicine” This study found that a herbal hair dye formulated with a 1:2 ratio of henna and indigo successfully colored unpigmented hair dark brown to black, with favorable attributes compared to synthetic dyes.
1 citations
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May 2006 in “Expert Opinion on Therapeutic Patents” This review summarizes 19 patents filed since 2000 for treating or preventing chemotherapy-induced alopecia, but reports no new clinical findings.
September 2025 in “Experimental & Molecular Medicine” This study observed that the small molecules KY19382 and KY19334 inhibited cancerous traits in human cutaneous squamous cell carcinoma cells by suppressing the Wnt/β-catenin pathway, indicating their potential as treatments for cancers involving CDK1 overexpression and diseases related to CXXC5 accumulation.
October 2024 in “International Journal of Research in Ayurveda and Pharmacy” This review investigates Jeemuta Bhringadi Taila, an Ayurvedic herbal oil formulation, exploring traditional claims of its benefits for hair health, skin issues, and other ailments by examining its ingredients and available scientific research, aiming to assess its relevance in modern healthcare.
1 citations
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January 2023 in “AYUSHDHARA” This paper reviews the Ayurvedic formulation Nilibhringadi Taila, which is claimed to improve hair quality and treat issues such as split hairs, premature greying, and baldness, and emphasizes the need for further research on its uses and effectiveness.
October 2023 in “Urologie in der Praxis” This article reviews the diagnostics and medical transition options for adults with gender incongruence, reports no new clinical results, and highlights the importance of primary care knowledge in managing these patients.
15 citations
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July 2004 in “AIDS” This case report describes a black HIV-2 patient who experienced reversible nail, hair, and skin hyperpigmentation linked to ritonavir-boosted indinavir therapy, which resolved after discontinuation.
2 citations
,
November 1995 in “American Journal of Obstetrics and Gynecology” This article reviews the need for multicenter clinical trials to establish reference data for ultrasound screening protocols for Down syndrome and reports no new findings.
179 citations
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May 1982 in “The Journal of clinical investigation/The journal of clinical investigation” This study found that plasma 3 alpha-diol glucuronide was markedly elevated in women with idiopathic hirsutism, suggesting it may be a marker of peripheral androgen action.
38 citations
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August 1999 in “New England journal of medicine/The New England journal of medicine” This letter discusses observations of indinavir's effects on skin, likening them to those of retinoids, but does not present new clinical findings.
15 citations
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March 2004 in “British Journal of Dermatology” This case report describes a 40-year-old Indian male with sclerosing cholangitis whose skin lesions and liver function improved following surgical treatment.
January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study reports that an intervention decreased glucose and insulin levels, indicating improved insulin resistance, which is linked to a skin condition called acne vulgaris and other disorders associated with insulin resistance.
74 citations
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July 1995 in “PubMed” This study suggests that reversible hypopigmentation in homocystinuric patients may result from tyrosinase inhibition by homocyst(e)ine, with in-vitro experiments showing copper sulfate reversing this inhibition.
July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” This study highlighted knuckle hyperpigmentation as an early sign of vitamin B12 deficiency, indicating a potential link to megaloblastic anemia in the vegetarian population in India.
January 2019 in “International Journal of Clinical & Medical Images” This clinical image report discusses a 50-year-old male with ethanol-related chronic liver disease who, despite showing signs of Dupuytren Disease, was asymptomatic and therefore did not receive treatment.
13 citations
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October 2017 in “Bioorganic & Medicinal Chemistry” This study found that compound 3, a tetrahydropyridoindole carboxymethylated at position 5, significantly inhibited sorbitol accumulation in both rat eye lenses and tissues affected by diabetes, indicating its potential as a lead compound for ALR2 inhibition.
17 citations
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January 2015 in “Dermatology online journal” This report describes a patient experiencing hair repigmentation linked to adalimumab therapy, a TNF inhibitor, a phenomenon not previously associated with this class of drugs.
January 2023 in “Brazilian Journals Editora eBooks” HPLC may detect prediabetes and diabetes earlier than Immunoturbidimetry because it shows higher A1c levels.
32 citations
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October 2004 in “Pharmacotherapy” In this study, peginterferon alfa-2b plus ribavirin therapy in hepatitis C patients was associated with serious adverse drug reactions in 20% of cases, highlighting differences from clinical trial findings.
June 2020 in “Jurnal Penyakit Dalam Indonesia” This case study highlights that primary biliary cholangitis in a patient with systemic lupus erythematosus can respond well to ursodeoxycholic acid therapy, and anti-DFS70 findings may require further evaluation for other nonsystemic autoimmune conditions.