4 citations
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September 2021 in “Sensors” In this study, LED therapy for eyebrow loss in older females with frontal fibrosing alopecia significantly increased eyebrow hair count after 10 treatments and maintained improvement at 6 months, indicating it could be a promising and well-tolerated treatment option.
3 citations
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February 2025 in “Life” In this study, significant improvements in skin density and thickness, especially around the lower eyelid, were observed across all age groups using plasma fractions from a single blood draw, indicating that the therapy's effectiveness may be age-independent.
2 citations
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May 2021 in “Clinical Pharmacology in Drug Development” This phase 1 study reported that after administering supratherapeutic doses of cortexolone 17α‐propionate, a topical antiandrogen intended for hair loss treatment, there was no effect on the QTc interval, indicating no measurable cardiac safety concerns in the concentration range tested.
2 citations
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November 2020 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” This article discusses the challenges and considerations in drug repurposing, particularly the importance of dose finding studies when adapting drugs for new indications, and reports no new clinical results.
2 citations
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May 2005 in “Seminars in Plastic Surgery” This article discusses the temporo-parieto-occipital flap for scalp reconstruction and reports no new clinical results; the authors emphasize its specific reconstructive indications.
1 citations
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December 2023 in “Plastic Surgery” In this study, pediatric patients who underwent tissue expansion surgery reported varying quality-of-life outcomes, with a median score of +17, and most would recommend the procedure despite some negative experiences, indicating the need for further research to understand factors influencing these outcomes.
1 citations
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November 2023 in “Naunyn-Schmiedeberg's archives of pharmacology” This review focused on the bioactive compounds and pharmacological properties of Lawsonia inermis (henna) and found that it contains various beneficial compounds with potential therapeutic applications, such as antioxidant and anti-inflammatory effects, indicating a need for further investigation into its medical benefits.
This source reports that modern hair transplant techniques, including follicular unit grafting, can create natural-looking results and are increasingly used beyond male pattern baldness to treat areas like eyebrows and scars, while even some controversial indications are being explored.
1 citations
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December 2014 This chapter reviews secondary uses for various drugs, noting that some have regulatory approval, indicating verified safety and efficacy, while others lack approval despite strong evidence.
August 2026 in “International Journal of Homoeopathic Sciences” This review explores the role of homeopathy, particularly the use of Phosphorus, for managing dandruff, noting current indications derive from traditional practices rather than modern trials, and emphasizes the necessity of well-designed studies to assess its effectiveness compared to conventional treatments.
May 2026 in “European Burn Journal” This systematic review concluded that the scalp can be a safe and effective donor site for split-thickness skin grafts in pediatric burn patients, with evidence indicating good scar quality and manageable complications, though a rigorous technique is essential to minimize risks.
February 2026 in “MDPI (MDPI AG)” This narrative review synthesizes findings suggesting that exosomes show promise for dermatological and regenerative applications, with early human studies indicating acceptable safety and potential benefits for wound care, rejuvenation, and alopecia, though clinical and regulatory development is still in its infancy.
January 2026 in “Annals of Clinical Endocrinology and Metabolism” This narrative review summarizes evidence on NAD⁺ biosynthesis and turnover, highlighting that while NAD⁺ precursors like NR and NMN consistently boost NAD⁺ levels in preclinical and human studies, clinical outcome results remain varied, indicating a need for more standardized human trials.
November 2025 in “Turkish Journal of Dermatology” This study found that both follicular unit transplantation (FUT) and follicular unit extraction (FUE) are safe and effective for female pattern hair loss, with FUE offering broader indications and higher patient satisfaction.
November 2025 in “Journal of Clinical Medicine” This narrative review examined the efficacy and safety of topical tretinoin for various dermatological conditions, finding strong support from robust trials for acne and photoaging, while indicating potential benefits for other uses like melasma and alopecia, yet highlighted the need for more standardized, high-quality trials.
October 2025 in “Journal of Drug Delivery and Therapeutics” In this review, the researchers compared the traditional use of Senna Makki in Unani medicine for various ailments to modern pharmacological evidence, endorsing its role as a laxative but indicating further research is needed for its efficacy in other therapeutic areas.
This study highlights that azelaic acid, initially recognized for skin hypopigmentation, shows potential in treating various skin conditions due to its complex mechanisms, even though these are not yet fully understood, indicating a need for further research.
October 2025 in “Journal of Cosmetic Dermatology” This study found that the AOPT-MTL mode is an effective and safe treatment option for nasal blackheads in Asians, indicating potential for widespread clinical use.
August 2025 in “DS Reviews of Research in Life Sciences” In this study, women with polycystic ovary syndrome showed significantly higher levels of DHEA, IL-6, and TNF-α compared to healthy controls, indicating a possible link between these biomarkers and PCOS.
August 2025 in “Systematic Reviews” This review identified significant effects of photobiomodulation therapy on pain reduction in burning mouth syndrome, disability in knee osteoarthritis, and fatigue in fibromyalgia, but noted that most outcomes had low-to-moderate certainty of evidence, indicating a need for further high-quality trials.
This paper reviews the current evidence regarding the off-label use of spironolactone for acne management, noting that despite its long-standing application in acne treatment, it has not yet received FDA approval for this indication.
January 2025 in “Organics” This study found that differently charged micelles influence the acid-base equilibria of cetirizine by altering its ionization constants, indicating potential interactions with biomolecules of various charges under physiological conditions.
In this review, the authors highlight that drugs promoting androgenic activity or inhibiting estrogenic activity may unmask or worsen androgenetic alopecia in genetically predisposed individuals, indicating the need for careful management in clinical settings.
March 2024 in “International Journal of Cosmetic Science” This study observed that dandruff-affected scalp skin has increased T-cell infiltration in the epidermis and a reduction in the hair follicle's physiological immune privilege, particularly in the suprabulbar outer root sheath area, indicating a distinct immune microenvironment compared to healthy scalp.
February 2024 in “Journal of Paediatrics and Child Health” This case report suggests the co-occurrence of systemic lupus erythematosus and an eating disorder in an adolescent may be linked through shared adolescent stress factors rather than neuropsychiatric lupus, despite algorithmic indications.
December 2023 in “Asian Journal of Pharmaceutical Research and Development” This research suggests that phytoestrogen-rich herbal extracts may help reduce hyperandrogenism, insulin resistance, and ovarian weight while promoting ovulation in polycystic ovarian syndrome, indicating potential for discovering new bioactive compounds.
November 2023 in “Circulation” In this case report, a 59-year-old man experienced recurrent pericardial effusion linked to minoxidil, with serologic indications of drug-induced lupus erythematosus, underscoring the need for clinicians to consider this rare complication of widespread minoxidil use.
August 2023 in “Dermatology and Therapy” This consensus statement from Saudi Arabia outlines evidence- and experience-based recommendations for diagnosing and managing alopecia areata, focusing on severity assessment, prognostic indicators, and therapeutic options, with special attention to pediatric patients and uncommon cases.
June 2023 in “Plastic and Reconstructive Surgery – Global Open” This review found that exosome use in aesthetic plastic surgery shows promise in areas like skin rejuvenation and hair restoration, with laboratory studies indicating enhanced outcomes, but clinical evidence remains largely anecdotal, and no exosome-based products have FDA approval.
April 2023 in “Journal of Investigative Dermatology” This study found that patients receiving PRP treatments for various types of alopecia and skin rejuvenation had a higher risk of adverse events and lower self-assessment scores when injections were administered at shallower depths, with significant correlations between patient and physician assessments across different indications.