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Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Alopecia Areata is linked to a higher risk of several diseases, which vary with age and sex.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Polycystic Ovary Syndrome (PCOS) symptoms vary globally, with bloating, high cholesterol, and glucose levels being common; the current diagnostic criteria may need refining.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Omega-6 and LDL cholesterol increase the risk of hair loss.

The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.

Irregular menstrual cycles in teenagers are linked to a higher risk of polycystic ovary syndrome and metabolic syndrome.

High BMI worsens hair growth in women with PCOS.

Testosterone therapy increases bone density in older men with low testosterone levels.

People with early hair loss may have higher insulin levels and a greater chance of developing metabolic syndrome.

Hair loss may increase heart disease risk.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

Androgenetic alopecia is linked to higher cardiovascular and metabolic risks, possibly due to irisin resistance.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Women with female pattern hair loss may have a higher risk of developing metabolic syndrome.

A woman with high testosterone and an adrenal nodule had an ovarian tumor causing her symptoms, which improved after the tumor was removed.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Women with early onset androgenetic alopecia have worse lipid profiles.