research Lignans and Neolignans: Plant Secondary Metabolites as a Reservoir of Biologically Active Substances
Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.
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research Aging of Hair
Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.
research Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox
Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
research Physiological Functions of PP2A: Lessons from Genetically Modified Mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
research Neurosteroids, Neuroactive Steroids, and Symptoms of Affective Disorders
Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
research Adverse Effects of Common Medications on Male Fertility
Some common medications can harm male fertility, but many effects can be reversed.
research Acne as a Chronic Systemic Disease
Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.
research A Current Review of the Cutaneous Manifestations of Renal Disease
Skin problems are very common in people with end-stage kidney disease.
research The Population Dynamics of Cancer: A Darwinian Perspective
Cancer development is like natural selection, involving mutated cells and environmental factors.
research Female Pattern Hair Loss: A Review Article
Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.
research Tcf3 Promotes Cell Migration and Wound Repair Through Regulation of Lipocalin 2
Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
research Male Androgenetic Alopecia
DHT, a testosterone byproduct, causes male pattern baldness.
research Selected Disorders of Skin Appendages: Acne, Alopecia, Hyperhidrosis
The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.
research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Premature Graying of Hair: Causes, Associations, and Treatments
Premature graying of hair may suggest health issues and currently lacks effective treatments.
research Hormonal Treatment of Acne Vulgaris: An Update
Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
research Tumor Mapping in Two Large Multigenerational Families With CYLD Mutations
CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
research Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research NUDT15, FTO, and RUNX1 Genetic Variants and Thiopurine Intolerance Among Japanese Patients With Inflammatory Bowel Diseases
Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.
research Prenatal Serological Diagnosis of Intrauterine Cytomegalovirus Infection
Blood tests confirmed a baby in the womb had a CMV infection.
research Trichoscopy in Hair Shaft Disorders
Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.
research Divergent Neuroactive Steroid Responses to Stress and Ethanol in Rat and Mouse Strains: Relevance for Human Studies
Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Spironolactone Versus Placebo or in Combination with Steroids for Hirsutism and Acne
Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.
research Therapeutic Potential of Patient iPSC-Derived Melanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia
Steroidogenic isoenzymes may help improve treatments for common hair loss.
research Thymosin Beta 4 Promotes Dermal Healing
Thymosin β4 helps improve skin healing and reduce scarring.
research Neonatal Finasteride Induces Anxiogenic-Like Profile and Deteriorates Passive Avoidance in Adulthood After Intrahippocampal Neurosteroid Administration
Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
research Finasteride Cream in Hirsutism
Finasteride cream reduces hair growth in women with hirsutism, but more research needed.