research Assessment of Occipital Involvement Among a Large Population of Females with Pattern Hair Loss in Saudi Arabia
About one-third of Saudi women with female pattern hair loss also have thinning hair at the back of their head.
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90-120 / 1000+ results research Synchronous Fluorescence as a Green and Selective Method for the Simultaneous Determination of Finasteride and Tadalafil in Dosage Form and Spiked Human Plasma
A new green method accurately measures finasteride and tadalafil in drugs and plasma.
research Efficacy, Tolerability, and Superiority of Propylene Glycol-Free, North American Witch-Hazel-Based Solution of 5% Minoxidil Sulfate for the Treatment of Female Androgenetic Alopecia
A witch-hazel-based 5% minoxidil solution is effective and safe for women with hair loss who didn't respond to regular minoxidil, especially if they're sensitive to propylene glycol.
research sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation
Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
research Polycystic Ovary Syndrome and Oxidative Stress: From Bench to Bedside
Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.
research Association Between Genetically Predicted Leukocyte Telomere Length and Non-Scarring Alopecia: A Two-Sample Mendelian Randomization Study
Shorter telomeres in white blood cells may increase the risk of a common type of hair loss.
research The Triacylglycerol Synthesis Enzyme DGAT1 Also Catalyzes the Synthesis of Diacylglycerols, Waxes, and Retinyl Esters
DGAT1 enzyme helps make diacylglycerols, waxes, and retinyl esters.
research Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack
Hair follicles prevent NK cell attacks to avoid hair loss.
research Functional Characterization of Soybean Strigolactone Biosynthesis and Signaling Genes in Arabidopsis MAX Mutants and GmMAX3 in Soybean Nodulation
GmMAX3b gene in soybeans boosts nodulation and affects hormone levels.
research Polycystic Ovary Syndrome (PCOS) Trilogy: A Translational and Clinical Review
The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.
research Pharmacological Mobilization of Endogenous Bone Marrow Stem Cells Promotes Liver Regeneration After Extensive Liver Resection in Rats
Using a drug to activate bone marrow stem cells can help the liver regenerate and function better after major surgery in rats.
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice: A Mechanistic Systematic Review
Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
research Adult Female Acne: Clinical and Therapeutic Particularities
Adult female acne is complex and requires a combination of treatments for effective management.
research Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome
PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research Cell Therapy for Androgenetic Alopecia: Elixir or Trick?
Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.
research Current Understanding and Treatment of Sex Hormone-Related Hair Diseases
Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.
research Post-Finasteride Syndrome Update: Point/Counterpoint
Finasteride's link to health issues like male breast cancer, infertility, and prostate cancer needs more research through placebo-controlled trials to confirm.
research The Biology and Genomics of Human Hair Follicles: A Focus on Androgenetic Alopecia
Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
research The Effect of DNMTs and MBPs on Hypomethylation in Systemic Lupus Erythematosus
Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.
research Androgen Receptor Antagonists Structure-Activity Relationships
Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
research Future Horizons in Hair Restoration
New cell-based therapies may improve hair loss treatments in the future.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research Clinical Efficacy of a Cosmetic Treatment by Crescina Human Follicle Stem Cell on Healthy Males with Androgenetic Alopecia
Crescina® lotion helps reduce hair loss and increase hair growth in males with androgenetic alopecia.
research Anti-Androgen Therapy in Female Adult Acne
Anti-androgens are safe and effective for treating moderate to severe adult female acne.
research Hirsutism: Diagnosis and Treatment
The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.
research A Peptide Derivative with Known Anti-Wrinkle Properties Identified as Potent Dipeptidylpeptidase-4 Inhibitor
A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.
research Repurposing a Clinical Antimalarial for the Therapeutic Induction of Lethal ER Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma
Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.
research Visualization of Sweat Suppression Following Botulinum Toxin A by Soluble Microneedle Arrays
Microneedle arrays deliver botulinum toxin effectively for sweat suppression, similar to injections.
research Hirsutism and Quality of Life
Hirsutism can lower a woman's quality of life, causing emotional distress and affecting social and work opportunities.