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A witch-hazel-based 5% minoxidil solution is effective and safe for women with hair loss who didn't respond to regular minoxidil, especially if they're sensitive to propylene glycol.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

Shorter telomeres in white blood cells may increase the risk of a common type of hair loss.

DGAT1 enzyme helps make diacylglycerols, waxes, and retinyl esters.

Hair follicles prevent NK cell attacks to avoid hair loss.

GmMAX3b gene in soybeans boosts nodulation and affects hormone levels.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

Using a drug to activate bone marrow stem cells can help the liver regenerate and function better after major surgery in rats.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Adult female acne is complex and requires a combination of treatments for effective management.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.

Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.

Finasteride's link to health issues like male breast cancer, infertility, and prostate cancer needs more research through placebo-controlled trials to confirm.

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.

Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

New cell-based therapies may improve hair loss treatments in the future.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Crescina® lotion helps reduce hair loss and increase hair growth in males with androgenetic alopecia.

Anti-androgens are safe and effective for treating moderate to severe adult female acne.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.

Microneedle arrays deliver botulinum toxin effectively for sweat suppression, similar to injections.

Hirsutism can lower a woman's quality of life, causing emotional distress and affecting social and work opportunities.

Hair transplantation is a treatment for hair loss mainly caused by genetics, with various techniques and potential complications, and results visible after 8-12 months.