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Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Testosterone improves mood and thinking skills; finasteride has no effect.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Eating less starch and dairy helped overweight women with PCOS lose weight and improve symptoms.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Eating healthy and exercising can help manage Polycystic Ovarian Syndrome and its related health problems.

The Garcinia Cambogia Nutri Bite could help manage PCOS symptoms.

The document explains how male reproductive hormones work and affect the body.

Sleep problems and skin issues affect each other; poor sleep can worsen skin conditions, and some skin treatments can improve or harm sleep quality.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

PCOS may have evolved as an advantage in past environments with food scarcity.

Parents often claim to use more home safety measures than they actually do.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Men with common hair loss (AGA) are more likely to have metabolic syndrome, which increases heart disease risk. Early screening could help prevent heart disease. More research is needed to understand this relationship better.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The Rotterdam Study aims to understand various diseases in older adults.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.