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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Low selenium intake may delay puberty in boys but not in girls.

Healthy lifestyle changes can significantly improve skin health as you age.

Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.

Most women with PCOS have insulin resistance, especially those with phenotype B.

Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

More research is needed to understand how testosterone is maintained in adult males.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Recognizing specific skin features helps diagnose and manage lupus erythematosus effectively.

Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.

Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

Troglitazone increases subcutaneous fat in lipodystrophy patients.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

More research is needed before using brown fat to treat polycystic ovary syndrome.

Higher potassium intake may protect against hair loss and liver fat in lysine-deficient rats.

Testosterone replacement therapy improved blood sugar and fat levels without raising prostate cancer risk in Japanese men with low testosterone.

Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.

Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.

The CORT, FGF5, and CD36 genes are crucial for the cold weather adaptation of Yanbian cattle.

Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Adults with polycystic ovary syndrome are much more likely to have obstructive sleep apnea.