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A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.

Certain factors can start hair growth in adult skin by making cells communicate and form new hair follicles.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

Hair and wool strength is affected by the number and type of bonds in their protein structures, with hair having more protein aggregates than wool.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

Finasteride doesn't affect bone density in male rats.

Finasteride doesn't affect bone density in male rats.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

Histone modification is key in treating chronic inflammatory skin diseases.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.

Mutations in the KRT85 gene cause hair and nail problems.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.

Plant extracts may help treat hormone-related hair loss.

A specific genetic marker is linked to male pattern baldness in Han Chinese men.

Skin cysts might help advance stem cell treatments to repair skin.

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

Combination therapy works best for female hair loss, increasing density and thickness.

Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.