research Targeted Gene Delivery to Skin Cells In Vivo: A Comparative Study of Liposomes and Polymers as Delivery Vehicles
Nonionic liposomes are the best for delivering genes to skin cells.
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research Hair Follicles Contribute Significantly to Penetration Through Human Skin Only Shortly After Application as a Solvent Deposited Solid in Humans
Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
research Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine
Caffeine applied to the scalp can protect hair follicles from UV damage.
research Delivery of Minoxidil Encapsulated in Cyclodextrins with Photoacoustic Waves Enhances Hair Growth
Using photoacoustic waves to deliver minoxidil improves hair growth effectively and safely.
research Efficacy of Topical Caffeine in Male Androgenetic Alopecia: A Systematic Review
Topical caffeine improves hair loss intensity, speed, and shedding, and works better with minoxidil/azelaic acid.
research Transfollicular Drug Delivery Systems
Transfollicular drug delivery can improve medication absorption through hair follicles.
research Use of Mass Spectrometry Imaging and a Full Thickness 3D Skin Equivalent for Evaluation of Percutaneous Absorption
The document concludes that various topical treatments show promise for skin conditions like atopic dermatitis, psoriasis, and hair loss.
research Microneedles as the Technique of Drug Delivery Enhancement in Diverse Organs and Tissues
Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
research Influence of Application Time and Formulation Reapplication on the Delivery of Minoxidil through Hairless Mouse Skin as Measured in Franz Diffusion Cells
Minoxidil absorption in skin is slowed by cleansing, depends on how long it stays on the skin, and is not much affected by reapplication.
research Bioactives in Nutricosmetics: A Focus on Caffeine from Tea to Coffee
Caffeine is beneficial for skin and hair treatments but needs better delivery methods to penetrate deeper skin layers.
research Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles
The new "differential stripping" method effectively measures how much substance gets into hair follicles.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
research Penetration and Distribution in Human Skin Focusing on the Hair Follicle
Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin
Topical oligonucleotide therapy targets hair follicles effectively.
research Topical Finasteride for the Treatment of Male Androgenetic Alopecia and Female Pattern Hair Loss: A Review of the Current Literature
Topical finasteride helps regrow hair and reduce hair loss in men and women.
research Hair Follicle Targeting with Nanoparticles
Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
research Topical Nanoemulgel: A Novel Pathway for Investigating Alopecia
Nanoemulgel could be a promising new treatment for hair loss.
research Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment
Microneedles help treat hair loss by improving hair surroundings and promoting growth.
research Particle Size Effect of Curcumin Nanocrystals on Transdermal and Transfollicular Penetration by Hyaluronic Acid-Dissolving Microneedle Delivery
Smaller curcumin nanocrystals penetrate skin and hair follicles better than larger ones.
research An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review
Better hair loss models needed for research.
research Investigation of Drug Partition Property in Artificial Sebum
The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
research Minoxidil and Dexamethasone Eluting Nanofiber Dressing for Cutaneous Wound Healing in Rat
The new wound dressing with minoxidil and dexamethasone could speed up healing and reduce scarring in rats.
research A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women
5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
research Penetration of Minoxidil from Ethanol/Propylene Glycol Solutions: Effect of Application Volume and Occlusion
More ethanol increases minoxidil delivery, but too much lowers efficiency.
research Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase
Minoxidil boosts hair growth by increasing blood flow and nutrients to hair follicles.
research Development and Characterization of Thiolated Cyclodextrin-Based Nanoparticles for Topical Delivery of Minoxidil
The new adhesive nanoparticles are effective for delivering Minoxidil to the scalp without skin irritation.
research Relative Influence of Ethanol and Propylene Glycol Cosolvents on Deposition of Minoxidil into the Skin
Ethanol over 50% helps minoxidil absorb better into skin.
research In Vitro, Ex Vivo, Penetration (EpiDerm) and in Vivo Dermatokinetics of Ketoconazole Loaded Solid Lipid Nanoparticles for Topical Delivery
Ketoconazole loaded solid lipid nanoparticles can penetrate skin better than regular drug suspension and marketed product, providing slow, sustained release and improved stability.
research Comparison of Two In Vitro Models for the Analysis of Follicular Penetration and Its Prevention by Barrier Emulsions
Pig ear skin is better than human skin for testing how well barrier creams block allergens from entering hair follicles.