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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Pityriasis rubra pilaris is a rare skin disorder with reddish-orange patches and thickened skin, needing better treatment understanding.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Early diagnosis and treatment of discoid lupus erythematosus improve outcomes.

Cyclosporine can cause a unique skin condition called "cyclosporine-induced folliculodystrophy."

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Treating cystoid macular oedema in uveitis is difficult and risky.

SLE is more common among Nigerians than previously thought, especially in women, requiring early treatment.

Women are more likely to have Lichen planopilaris, and treatments with cyclosporine and methotrexate are most effective but less safe than mycophenolate mofetil.

Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.

Contact sensitizers like DCP and SADBE are the most effective treatments for alopecia areata.

Skin symptoms are important for diagnosing and managing juvenile-onset systemic lupus erythematosus and usually get better with treatment.

No treatment is completely effective for alopecia totalis and alopecia universalis.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Oral valganciclovir improved a patient's skin condition caused by immunosuppression.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Myositis in lupus patients is linked to skin rash, hair loss, blood issues, and high disease activity.

A disease causing skin issues in young adult German short-haired pointers is hereditary, with most affected dogs not responding to treatment.

Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.

SLE patients in eastern Saudi Arabia have a generally good prognosis despite multi-organ involvement.

Patients with chronic skin conditions on systemic treatments did not have worse COVID-19 outcomes and could resume their treatments after recovery.

Two transplant patients on cyclosporine unexpectedly developed hair loss.

Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.

Leflunomide successfully treated a rare skin condition in a liver transplant patient.

Use antimalarials like hydroxychloroquine for cutaneous lupus, avoid herbal supplements, and focus on lifestyle changes like sun protection.

The decision board effectively helps lupus nephritis patients in Brazil choose treatments by clearly presenting options and side effects.

Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.

Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.

Patients with chronic graft-versus-host disease often have skin problems like vitiligo and alopecia areata.

Effective wound healing after HS treatments can be achieved with various methods like moist dressings and skin grafting.