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This study suggests that enhancing glycolysis in MSCs may improve their immune functions and therapeutic potential, although more evidence is needed to understand the direct metabolic mechanisms involved.

This review found that adding immune checkpoint inhibitors to cancer treatment regimens likely increases the incidence of specific drug-related skin toxicities in adult Asian patients, highlighting the need for careful monitoring and management strategies.

This study found that topical application of FK506 stimulated hair growth in animals, which may occur independently of its immunosuppressive effects, though its effect on human hair growth remains unclear.

This review summarizes the pathophysiology and immune mechanisms of inflammatory skin diseases like psoriasis and atopic dermatitis, highlighting the therapeutic potential of targeted immunotherapies, but reports no new clinical results.

In this study, 37.5% of patients with nodal or metastatic cutaneous melanoma treated with immune checkpoint inhibitors developed skin adverse events, primarily low-grade rashes, vitiligo, and other dermatological symptoms, occurring mainly after 10 weeks of treatment.

This review summarizes current evidence on the use of contact immunotherapy, excluding alopecia areata, for various skin diseases, discussing its safety, efficacy, and the underlying mechanisms as reported from studies in the PubMed database.

This study found that methotrexate treatment for 15 days suppressed tuberculin hypersensitivity in Strain 2 guinea pigs without causing lymphopenic or anti-inflammatory effects.

In this review, researchers explored the design of composite biomaterials for immunomodulation and their potential to influence immune cell behavior, which could be leveraged for treating diseases like cancer and improving tissue regeneration, while also addressing translational challenges such as biocompatibility and safety.

This article reviews the therapeutic use of interferons and other cytokines in various viral, tumorous, and inflammatory diseases, discussing their biological effects and potential future applications without presenting new experimental results.

This study observed that patients receiving IL-2 immunotherapy developed a skin eruption characterized by burning and pruritus, which resolved shortly after stopping the infusion, suggesting that IL-2 mediated these effects.

In a murine model of alopecia areata, this study observed that the IL-2 fusion protein HCW9302 helped prevent disease development by expanding regulatory T cells and reducing disease-causing effector T cell infiltrates, suggesting potential for using IL-2 fusion proteins in alopecia areata treatment.

Enhancing Tregs can protect against alopecia areata.

This study found that UV exposure in human skin induces IL-10 production by macrophages, while Langerhans cells are depleted and their IL-12 production is downregulated.

This study reported that immunotherapy in cancer patients can lead to skin-related immune adverse events, such as rashes, pruritus, and vitiligo, affecting a substantial proportion of patients.

This review discusses recent advancements in targeted therapies for vitiligo, including JAK inhibitors and mesenchymal stem cells, and highlights the need for further research.

The study introduced an advanced skin model, ImmuSkin-MT, which effectively distinguished between different strengths of skin sensitizers by mimicking the interaction of immune cells in skin tissue.

This review discusses the unique advantages and challenges of microneedle arrays for vaccine and immunotherapy delivery but reports no new clinical results.

This study highlights the role of immune dysregulation, microRNA modulation, and SIRT1 pathways in alopecia areata, suggesting antisense oligonucleotides targeting miR-485-3p as a promising therapeutic strategy for promoting hair regrowth and reducing inflammation in murine models.

This research paper reviews the mechanisms and management of non-biologic immunosuppressive drugs used in dermatology, highlighting their safety profiles and handling during pregnancy, breastfeeding, and vaccination, but does not report specific results on these aspects.

This letter to the editor discusses immune checkpoint inhibitor-related alopecia and insights into its pathophysiology using non-invasive diagnostic techniques, but reports no new clinical results.

This study reports that while systemic immunotherapies are often used for immune-mediated hair loss, they may also be considered for treating androgenetic alopecia when it coexists with immune-related conditions like alopecia areata.

This study highlights that biological therapy, which stimulates the immune system through various methods like cytokine injections and immune checkpoint inhibition, shows promise for treating melanoma based on laboratory and clinical studies.

This article reviews the potential of low-dose cytokine therapy for treating vitiligo and psoriasis, citing its promising applications but offering no new clinical results.

Immunosuppression therapy with methylprednisolone effectively treats childhood alopecia areata.

In this study, researchers explored the immunological mechanisms involved in alopecia areata and suggested that targeting immune responses, particularly using JAK inhibitors and other immunomodulatory drugs, could help achieve stable remission and improve patients' quality of life.

This review discusses the cosmetic use and safety of Hypericum Perforatum Extract and Oil, finding that current data are insufficient to support their safety in formulations due to a lack of comprehensive testing.

This article discusses the broad traditional uses and potential pharmaceutical applications of burdock, recommending the development of new products but reporting no experimental findings.

New retinoids are effective for various skin conditions and are being developed to have fewer side effects.

This mini-review details how the SOX family of transcription factors contributes to cancer immune evasion by affecting antigen presentation, impacting the tumor's immunosuppressive environment, and regulating immune checkpoints, offering insights for developing novel immunotherapy strategies.