Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that the expression of laminin-511 and -332 was significantly increased in psoriasis skin lesions and may influence keratinocyte proliferation and apoptosis, suggesting a previously overlooked role in the disease's pathogenesis.

This study observed that nicotinamide can effectively inhibit human hair growth and promote hair follicle regression in cultured human scalp models without negatively affecting epidermal vitality, suggesting its potential as a hair growth inhibitor in cosmetic applications.

In this study, finasteride was found to inhibit the dopaminergic system and reduce open-field behaviors in adolescent male rats by decreasing dopamine levels and related proteins.

In this study, topical application of Hominis Placenta significantly promoted hair regrowth and increased hair density in C57BL/6 mice, suggesting its potential as a treatment for alopecia.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

This review updates on the development of liposomal carriers for delivering growth factors to improve tissue regeneration and highlights recent efforts to enhance their stability and retention in tissues.

This study found that inhibiting the TRPV3 channel may significantly promote hair growth and suggests a potential therapeutic approach for hair loss and related skin diseases.

This study found that doxorubicin induces hair follicle apoptosis through TRAIL receptor signaling, providing insights for managing chemotherapy-induced hair loss.

This study observed high expression of mTOR pathway effectors in fibrous papules and TSC-associated angiofibromas, suggesting that topical rapamycin might be an effective treatment for fibrous papules.

Dutasteride reduces DHT more effectively than finasteride.

This review discusses differences in ERβ signaling between rodents and humans and reports no new clinical results; the authors highlight the need for further research in humans before using ERβ agonists clinically.

This study found that manipulating SIMK expression in alfalfa affects root hair growth, infection thread and nodule formation, and overall plant biomass, highlighting its potential biotechnological applications.

This review discusses the current knowledge on using special and immunohistochemical stains for diagnosing hair disorders, concluding that no stains are recommended for routine use in hair pathology.

This study found that the prevalence of hyperprolactinaemia in healthy premenopausal female blood donors is low and not affected by hormonal contraceptive use, with stress-related factors being the most common cause.

This study suggests that Ptprq in the hair bundles may exist as multiple isoforms that are differentially expressed throughout development and affect the organization of stereocilia in the chick inner ear.

This review discusses the role of oestrogens in stimulating linear bone growth and pubertal changes in both boys and girls, highlighting their influence on the growth hormone-insulin-like growth factor axis; it reports no new clinical results.

This article discusses the role of suction-assisted lipectomy (SAL) and the hCG method in obesity management, highlighting the speculative benefits of hCG but reporting no new clinical findings.

This study suggests that the gene rs27647 polymorphism may play a role in the pathogenesis of severe acne vulgaris in post-adolescent male patients.

This study found that finasteride treatment in male rats altered steroid hormone homeostasis and caused kidney damage, suggesting potential risks for patients with renal dysfunction on androgen or antiandrogen therapy.

This study suggests that PDCD4 regulates keratinocyte proliferation and contact inhibition, playing a role in epidermal homeostasis and wound healing.

This study found that patients with alopecia areata and androgenetic alopecia showed increased c-kit expression and decreased Ki-67 expression in hair follicle cells compared to controls, suggesting a possible feedback mechanism involving stem cell factor signaling.

The researchers reported that the antipsoriatic compounds 1,25-dihydroxy-vitamin D3 and calcipotriol thinned the living cell compartment in organotypic ORS cultures by accelerating the differentiation pathway rather than affecting proliferation.

This study developed dissolving microneedles using specific polymers for transdermal delivery of rizatriptan benzoate, demonstrating improved drug skin penetration and significant alleviation of migraine symptoms in vivo compared to passive diffusion, suggesting potential advantages over conventional treatment methods for acute migraine.

This study found that systemic administration of NDP-MSH, a melanocortin receptor agonist, provided neuroprotective effects on dopaminergic nigrostriatal neurons in a mouse model of Parkinson's disease, reducing neuroinflammation and suggesting a role for regulatory T cells in these neuroprotective effects.

This review discusses the current and emerging methods for profiling skin microbes to advance our understanding of the microbiome in skin disease, but it reports no new clinical findings.

This study found that Sox10 may play a role in early hair follicle development and cycling, as it is expressed in specific regions of the hair follicle during different phases of the hair cycle in mice.

In this study, PGD2 was shown to increase testosterone production in human keratinocytes through reactive oxygen species, suggesting potential benefits of antioxidants like N-acetyl-cysteine for AGA patients.

This study suggests that uncontrolled embryonic trichogenesis may play a role in the development of trichoblastoma in rabbits.

This study found that cyclosporine A's enhancement of hair growth in mice is partly due to its ability to block the nuclear translocation of apoptosis-inducing factor, slowing the hair follicle transition to the catagen phase.

This study found that variations in the androgen receptor gene influenced memory function in women, with GGN repeat polymorphisms significantly affecting logical memory performance only in females.