39 citations
,
May 2019 in “Journal of the American Academy of Dermatology” This study found that nonscarring alopecia in patients with systemic lupus erythematosus may indicate higher disease activity, as evidenced by specific histological and immunofluorescence changes.
51 citations
,
May 1984 in “Journal of the American Academy of Dermatology” In this study, the authors observed that cell-mediated immune mechanisms may be involved in the pathogenesis of benign follicular mucinosis, based on the cellular and immunological characteristics of two patient cases.
January 2026 in “IECCMEXICO” This review highlights how chronic inflammatory skin disorders like psoriasis and atopic dermatitis may be better understood as manifestations of systemic immune dysregulation rather than just skin issues, suggesting that recognizing these conditions as markers of broader immune imbalance can improve diagnosis and medical education.
41 citations
,
November 1993 in “Journal of The American Academy of Dermatology” This study found that DPCP treatment led to cosmetically acceptable hair regrowth in 38% of patients with chronic severe alopecia areata, while adding 5% minoxidil showed no significant clinical benefit.
14 citations
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March 2014 in “Journal of The American Academy of Dermatology” In this study, symmetrical acrokeratoderma was observed to frequently occur alongside ichthyosis vulgaris, with no specific therapy available for the condition.
30 citations
,
July 2019 in “PloS one” This study found that T-regulatory cells, specifically the FOXP3 CD39 subset, were significantly reduced in both circulation and hair follicles of alopecia areata patients compared to healthy subjects, suggesting potential therapeutic targets.
21 citations
,
March 2019 in “Experimental Dermatology” This review discusses the role of perifollicular macrophages in hair growth and suggests targeting them could be relevant for managing hair growth disorders, but reports no new results.
421 citations
,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
33 citations
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July 1992 in “Journal of Investigative Dermatology” Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.
23 citations
,
December 1990 in “PubMed” This case study suggests that systemic lupus erythematosus should be considered as a potential diagnosis for immune-mediated skin disease in horses, based on multisystemic signs and specific histopathologic and immunopathologic findings.
13 citations
,
January 2018 in “BioMed Research International” This review summarizes recent findings on scalp involvement in pemphigus vulgaris and pemphigus foliaceus, highlighting diagnostic methods and their underlying histopathological, immunopathological, and clinical features, but reports no new clinical results.
1 citations
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April 2022 in “JAAD case reports” This case report describes a unique instance of IgG/IgA pemphigus in a Chinese woman, highlighting its distinct clinical and immunopathologic characteristics, including successful management with dapsone and prednisolone.
Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.
2 citations
,
January 2004 in “Elsevier eBooks” This article reviews historical uses of the term "lupus" for various skin disorders but provides no new clinical findings.
August 2025 in “Cosmetics” This review discusses the possible link between cosmeceuticals and frontal fibrosing alopecia but reports no conclusive findings; the authors stress further research on environmental triggers is needed.
2 citations
,
June 2021 in “Immunopathologia Persa” This study observed that among Iranian patients with rheumatoid arthritis, methotrexate treatment was discontinued or reduced in nearly half of the cases due to side effects such as nausea, flu-like symptoms, hepatotoxicity, and hair loss, with hepatotoxicity linked to higher doses and longer treatment duration.
11 citations
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October 2011 in “Allergologia et immunopathologia” A girl with Netherton syndrome was able to eat wheat without allergies after a special treatment.
November 2025 in “Allergologia et Immunopathologia” This case report documents a rare incident where total alopecia developed within ten days of a bee sting, in the absence of hypersensitivity reactions, suggesting that bee venom may have an immunomodulatory or exacerbating effect on the immune system.
15 citations
,
January 2022 in “Immune Network/Immune network” This review summarizes the pathophysiology and immune mechanisms of inflammatory skin diseases like psoriasis and atopic dermatitis, highlighting the therapeutic potential of targeted immunotherapies, but reports no new clinical results.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” Skin lymphoproliferative disorders are hard to diagnose and often linked to systemic diseases, but most have a good prognosis with accurate diagnosis.
January 2024 in “Wiadomości Lekarskie” This study outlines new strategies for overcoming "cold" tumors, which are typically unresponsive to cancer immunotherapy, with approaches like dendritic cell-based treatments and local immune microenvironment modification, bolstered by both preclinical and clinical trial data.
May 1991 in “Current problems in dermatology” This article reviews the relationship between the skin and the immune system and discusses how skin manifestations can indicate immunodeficiencies but reports no new research findings.
October 2025 in “Transactions on Materials Biotechnology and Life Sciences” This study reviews the mechanisms and recent findings of immunotherapies for NSCLC, highlighting their potential to improve treatment outcomes and reduce side effects compared to traditional therapies.
10 citations
,
January 2013 in “Clinical and developmental immunology/Clinical & developmental immunology” This article is a special issue that reviews current research on the pathogenesis, diagnosis, and treatment of systemic autoimmune diseases, but it does not present new results.
11 citations
,
September 1999 in “Journal of the European Academy of Dermatology and Venereology” This review examines various immunomodulatory therapies for cutaneous lymphoma and notes that they are most effective in the disease's early stages.
54 citations
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January 1986 in “Medical clinics of North America/The Medical clinics of North America” This study reviewed pathology reports of patients with multiple myeloma and found that skin biopsies commonly show graft-versus-host disease, drug-related lesions, and Sweet's syndrome, especially related to transplantation timing.
8 citations
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January 1990 in “Immunology Today” May 2024 in “Frontiers in Medicine” Targeted immunological therapies offer safer and more effective treatments for skin conditions like eczema and psoriasis.
December 2021 in “International Journal of Biology Pharmacy and Allied Sciences” This article discusses various autoimmune diseases, including their symptoms and management, and reports no new clinical findings.
This article reviews the cutaneous side effects of immune checkpoint inhibitors and targeted therapies for skin cancers, noting that while generally mild, these effects can influence treatment decisions and quality of life, underscoring the need for physicians to be aware of these adverse reactions.