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This review discusses the current evidence on platelet-rich plasma therapy's biological mechanisms and clinical applications, highlighting its promise in regenerative medicine and the challenges to its integration in nursing practice.

This systematic review synthesizes evidence from the past 20 years to highlight the potential of exosome-based therapies from stem cells and plants in improving cutaneous repair, skin aging, and challenging dermatological conditions through mechanisms like immunomodulation and collagen remodeling.

This review discusses current knowledge of keratinocyte stem cell dynamics, including their regenerative roles and potential applications beyond wound healing, but presents no new clinical findings.

This study highlights that while advances in dermatology, such as biologics and JAK inhibitors, have improved treatments for conditions like atopic dermatitis and psoriasis, challenges remain, including issues with lasting efficacy and the need for more personalized therapies.

This study reviews the role of exosomes in regenerative aesthetics, highlighting their potential in treating conditions like photoaging and wound healing through mechanisms like matrix remodeling and immunomodulation, while also noting advancements in exosome isolation techniques and regulatory considerations.

This review highlights recent advancements in engineered probiotics for wound healing, reporting that genetically engineered strains of Lactobacillus reuteri and Lactococcus cremoris have shown promise in promoting faster wound healing in pre-clinical and clinical settings, particularly for diabetic foot ulcers.

This review suggests that the inner root sheath of human hair follicles may have broader regulatory roles beyond structural support, potentially impacting processes like folliculogenesis, anagen phase regulation, and immunomodulation.

This review discusses the use of adipose tissue and platelet-rich plasma in tissue repair and regeneration, noting their promise in surgical outcomes but emphasizing the need for further research to optimize therapies.

This case study from Ukraine describes a 5-year-old Akita dog diagnosed with sebaceous adenitis, presenting with pruritus, alopecia, and inflammation; treatment over 30 days led to complete restoration of affected areas, implicating potential heritability in Akitas.

This review highlights the potential of exosomes, particularly those derived from mesenchymal stromal cells, for treating skin conditions and regeneration, but it also identifies challenges in their production and application.

This review examines the mechanisms, recent findings, and strategies to enhance mesenchymal stem cells' therapeutic effects in skin wound healing, but reports no new research results.

In this chapter, researchers discuss how microRNAs (miRNAs) interact with vitamin D signaling, highlighting their emerging role as mediators in vitamin D-regulated disorders and their potential for developing miRNA-based clinical applications.

This chapter reviews the clinical evidence of adding platelet-rich plasma to lipofilling for tissue regeneration, with suggestions of benefits in skin rejuvenation and wound healing, but lacks well-designed trials.

This research suggests that superficial cryotherapy is a safe and nearly as effective alternative to topical steroids and PUVA therapy for treating alopecia areata, especially in children.

Bulge progenitor cells show promise for regenerating hair follicles and increasing hair density.

This review discusses current advancements in mesenchymal stem cell-based therapies for skin repair and rejuvenation, focusing on therapeutic strategies, particularly highlighting the potential of neonatal and placenta-derived MSCs, and reports no new clinical results.

This review discusses the therapeutic potential and challenges of using extracellular vesicles derived from mesenchymal stem cells, concluding that they may have a comparable therapeutic potential to the original cells despite current challenges in their application and production.

This review discusses recent advancements in nanotechnology for treating hypertrophic scarring and atopic dermatitis, highlighting the potential of nanotherapeutic platforms in enhancing therapeutic effects by modulating the skin's microenvironment.

This review highlights that both human-derived and plant-derived exosomes show anti-inflammatory and antioxidant properties, with human exosomes being better for targeted medicinal treatments due to their ability to transport healing drugs, while plant exosomes are more scalable and cost-effective for cosmetic applications.

This study found that tumor immunotherapy, while effective against solid tumors, can disrupt the immune balance in hair follicles, causing follicular toxicity and alopecia, highlighting the need for targeted interventions to manage these adverse effects.

This review discusses the molecular mechanisms and clinical applications of autologous platelet-derived products for TMJ regeneration, but reports no new clinical results.

In this perspective, recent advances in regenerative medicine, including bioartificial substitutes and engineered in vitro platforms, are reviewed for their potential to restore human hair follicles, highlighting new technologies like 3D printing, hair-on-a-chip models, and stem cell-derived organoids.

This study found that in patients with Alopecia Areata, CD27 and IL-35 levels were significantly higher in those with bacterial infections, suggesting they may be useful as immunological biomarkers.

This review explores the potential of mesenchymal stem cells in skin regeneration and rejuvenation, highlighting their ability to modulate immune response and enhance extracellular matrix strength but does not provide new clinical evidence.

This article reviews the potential and limitations of cryotherapy for alopecia areata in middle-aged patients and highlights the need for further research, without reporting new clinical findings.

This study analyzed the therapeutic potential of various plant species for alopecia areata treatment, highlighting their possible benefits due to anti-inflammatory and immunomodulatory properties, though more research is needed to fully understand the mechanisms involved.

This source reports that for treating keloids and hypertrophic scars, combination pharmacotherapy targeting multiple sites is generally more effective than using a single drug, though outcomes of individual therapies vary and the development of satisfying treatments is ongoing.

This study by Refat et al. found that the level of CD8+ T cell infiltrates in vitiligo lesions before surgical treatment can predict the likelihood of successful repigmentation, suggesting a potential new method for identifying patients who may benefit the most from surgical interventions.

This chapter reviews the potential of stem cells from discarded deciduous teeth in regenerative medicine and dentistry, with no new clinical results presented.

This review discusses immunomodulatory formulations to address post-COVID conditions and reports no new clinical findings.