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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

Garlic can help hair grow by activating certain growth pathways, and it works whether you eat it or apply it to your scalp.

A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.

New therapies are being developed that target integrin pathways to treat various diseases.

OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.

Ginsenoside Rg4 from ginseng may help hair growth by activating certain cell signals.

People with alopecia areata may also have allergic rhinitis and should be checked for respiratory allergies.

The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

The skin is a large organ that plays a role in the immune system.

Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.

A protein called FERONIA helps control root hair growth in response to cold and low nitrogen by activating nutrient-sensing pathways in a plant called Arabidopsis.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Rumex japonicus Houtt. may be an effective treatment for atopic dermatitis by reducing inflammation.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Skin aging reflects overall body aging and can indicate internal health conditions.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

New alopecia treatments aim for better results and fewer side effects.