November 2024 in “International Journal of Molecular Sciences” In this review, the authors discuss how hair may protect against scalp skin cancer by enabling IL-17-biased immunosurveillance, while hair loss could permit tumor development by reducing this immune protection.
September 2024 in “Preprints.org” In this review, the authors propose that hair on the scalp may protect against non-melanoma skin cancer by maintaining an IL-17 biased immunosurveillance, with hair loss potentially increasing the risk of skin cancer due to disrupted immune monitoring.
September 2024 in “Pigment International” Results are not reported in this abstract; it discusses recent advancements in understanding vitiligo's pathogenesis, treatment, and comorbidities, emphasizing emerging areas like gut microbiome involvement and highlighting the disease's reclassification as a systemic condition with evolving therapies.
May 2024 in “Trends in endocrinology and metabolism” This research review discusses how iron deficiency affects various bodily functions and systems, such as immunity and metabolism, by identifying the iron-dependent enzymes and pathways involved, suggesting that understanding these mechanisms may offer new treatment possibilities for related diseases.
January 2024 in “International Journal of Dermatology” This commentary piece identifies interleukin-13 as a potential therapeutic target for treating alopecia areata associated with atopic dermatitis, although specific study results or outcomes are not provided in the abstract.
September 2023 in “International Journal of Trichology” In this study, researchers reported three cases of alopecia areata patients experiencing a rare targetoid pattern of hair regrowth, a phenomenon originally described in 1988.
This article reviews the nutritional needs and challenges for the elderly, emphasizing the benefits of antioxidants and healthy fats for immune support and overall health, but presents no new clinical results.
February 2023 in “Pakistan Journal of Medical and Health Sciences” This study found a variety of dermatological conditions in pregnant women, with Striae Gravidarum being the most prevalent at 48.1%, followed by Linea Nigra at 45.9%.
March 2020 in “Poster presentations” This case report describes a patient with unrecognized systemic lupus erythematosus, who experienced myocarditis, polyneuropathy, and pericarditis, and recovered following cardiac support and medication.
January 2018 in “Journal of Diabetic Association Medical College.” This case study reports a two and a half-month-old with biotinidase deficiency who showed rapid seizure improvement with biotin treatment after presenting with convulsions and neurological symptoms.
February 2012 in “Australasian Journal of Dermatology” Some moles can disappear naturally, maintenance therapy for Stage 1 mycosis fungoides may not be necessary, allergic skin reactions in children are rising, weekly methotrexate for psoriasis is more effective than daily, long-term finasteride use improves hair growth with few side effects, and petrolatum improves UV therapy for psoriasis.
December 2002 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” This study investigated a potential link between male pattern baldness and Pityrosporum group fungal contamination but found no significant statistical association.
7 citations
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April 2024 in “Skin Research and Technology” This study found that ChatGPT provided fairly accurate answers to common psoriasis-related questions, as rated by medical experts, although it doesn't fully replace professional medical judgment or diagnosis.
October 2014 in “Journal of the Portuguese Society of Dermatology and Venereology” This paper presents a therapeutic approach with excellent results in a case of lichen planopilaris overlapping with dermatomyositis and scleroderma, although broader applicability is not discussed.
3 citations
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October 2011 This article discusses revised SLE classification criteria by the SLICC and reports no new research results.
1 citations
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January 2024 in “ACS Medicinal Chemistry Letters” This Patent Highlight discusses recent progress in developing TYK2 inhibitors, which show potential for treating conditions like cancer, alopecia areata, and psoriatic arthritis.
May 2015 in “Journal of The American Academy of Dermatology” This study suggests that blood microarray biomarkers may help predict individual treatment response in psoriasis patients, highlighting a distinct blood signature related to inflammation, interferon, and myeloid lineage transcripts.
4350 citations
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May 2012 in “Arthritis & Rheumatism” This study found that the new SLICC classification criteria for systemic lupus erythematosus were more sensitive and resulted in fewer misclassifications than the current ACR criteria, although they had lower specificity.
1113 citations
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August 1999 in “The New England Journal of Medicine” This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.
463 citations
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September 2004 in “Clinics in dermatology” This review discusses the development, function, and complex roles of sebaceous glands in acne and suggests future acne treatments should target inflammation and lipid production; it reports no new clinical results.
356 citations
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December 1986 in “The journal of cell biology/The Journal of cell biology” This study found that specific human hair keratins are differentially expressed in the hair follicle, suggesting a shared pathway of epithelial differentiation between hair cortex and nail plate cells.
126 citations
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October 1998 in “Experimental Dermatology” This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.
102 citations
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December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses the role of immune privilege collapse in the pathogenesis of alopecia areata, emphasizing the potential for therapeutic manipulation of hair bulb immune privilege to offer new treatment options, and reports no new results.
86 citations
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December 2001 in “Experimental dermatology” This review classifies mutant mice with hair abnormalities into six categories, providing an annotated table that serves as a reference for understanding the molecular controls of hair growth.
78 citations
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January 2013 in “Dermatology Online Journal” This review discusses various diseases associated with hidradenitis suppurativa, including obesity, arthritis, and pyoderma gangrenosum, but reports no new clinical results and calls for further research.
77 citations
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April 2016 in “British journal of dermatology/British journal of dermatology, Supplement” This article reviews the role of IL-17 in inflammatory skin disorders and highlights its potential therapeutic targeting in both neutrophilic and lymphocyte-mediated conditions, reporting no new experimental results.
69 citations
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June 2017 in “Experimental Biology and Medicine” This review discusses the advancements and challenges in developing in vitro human skin models incorporating components like vasculature for drug testing and disease research, but reports no new clinical results.
56 citations
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October 2016 in “Journal of dermatological science” This review explores multidisciplinary advances in understanding alopecia areata, including epidemiology, pathogenesis, and innovative treatments, but reports no new research results.
53 citations
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June 1983 in “Journal of Investigative Dermatology” This study reports that human epidermal transglutaminase activity increases with treatment using organic solvents and chemicals without significant molecular weight changes, which may allow modulation of the enzyme in skin diseases.
53 citations
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December 2012 in “Revista da Sociedade Brasileira de Medicina Tropical” In this study, liver transaminase levels and various symptoms persisted in some adult dengue patients even two months after diagnosis.