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The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

ERG increases SOX9, promoting prostate cancer growth and invasion.

BMAL1 controls skin cell growth and UV damage risk, peaking at night.

miR-31 regulates hair growth by controlling gene expression in hair follicles.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

A new 3D culture system helps grow and study mouse skin stem cells for a long time.

Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Stress may trigger hair loss by affecting immune protection in hair follicles.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.

Neuregulin3 affects cell development in the skin and mammary glands.

SIRT7 protein is crucial for starting hair growth in mice.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.

Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.

Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.

sPLA2-X is crucial for normal hair growth and follicle health.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.