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Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Cancer development is like natural selection, involving mutated cells and environmental factors.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.