83 citations,
June 2018 in “Frontiers in immunology” Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
60 citations,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
58 citations,
January 2013 in “The Journal of Clinical Endocrinology and Metabolism” Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
36 citations,
January 2017 in “Journal of Obstetrics and Gynaecology Research” The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.
33 citations,
January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
31 citations,
April 2019 in “Experimental and Therapeutic Medicine” β-blockers can cause skin problems like psoriasis and vitiligo, and doctors should tell patients about these risks.
31 citations,
July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
28 citations,
October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
28 citations,
December 2018 in “Plant, cell & environment/Plant, cell and environment” A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.
27 citations,
April 2018 in “Journal of autoimmunity” iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.
24 citations,
May 2018 in “Journal of Molecular Endocrinology” The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
23 citations,
March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
23 citations,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
23 citations,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride helps hair growth by decreasing cell death in hair follicles.
22 citations,
June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
21 citations,
October 2018 in “European Journal of Pharmacology” Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.
21 citations,
November 2017 in “Livestock science” Nellore cattle have genetic variations linked to their adaptation to tropical environments.
19 citations,
December 2019 in “Steroids” Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
18 citations,
October 2014 in “Experimental Dermatology” Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.
16 citations,
September 2018 in “Scientific reports” Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
15 citations,
January 2018 in “Biomedical Reports” Exosomes are important for skin health and could help diagnose and treat skin diseases.
14 citations,
July 2021 in “Biomedicines” Platelet-rich treatments can help improve wound healing and tissue repair.
13 citations,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
11 citations,
July 2021 in “Nanomaterials” Wound covers with α-13'-COOH from vitamin E can improve and speed up wound healing.
10 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
9 citations,
December 2020 in “Dermatologic Therapy” Certain drugs are effective for skin conditions like psoriasis, vitiligo, and hair loss.
8 citations,
May 2022 in “Journal of medicine and life” COVID-19 patients may experience hair loss, but it's not linked to their age or sex.
8 citations,
January 1989 in “Annual Reports in Medicinal Chemistry” Hair loss from alopecia areata and androgenetic alopecia can be treated, but more effective and safer treatments are needed.
7 citations,
January 2017 in “American Journal of Biological Anthropology” Sardinians were historically short due to a mix of genetics and factors like disease and poor nutrition, but recent height increases suggest better living conditions had a bigger impact.
6 citations,
September 2005 in “Expert Opinion on Pharmacotherapy” Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.