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This review provides an overview of caffeine's effects on cancer, cardiovascular, immunological, inflammatory, and neurological diseases, highlighting both its potential benefits, such as neuroprotection and anti-aging, and possible adverse effects like elevated blood pressure, anemia, and migraine.

This study found that in a rat model, 14,15-EET may alleviate central poststroke pain by enhancing thalamic inhibition through neurosteroid signaling, potentially outperforming gabapentin in early-stage treatment.

This study reports that drug repurposing for COVID-19 has had mixed results, with success for some drugs but a lack of clinical efficacy for others, highlighting the need for improved preclinical profiling and a standardized drug development platform for future antiviral treatments.

In this exploratory study of trigeminal neuralgia patients undergoing microvascular decompression surgery, differential protein expression in plasma and cerebrospinal fluid was observed between responders and non-responders, suggesting potential biomarkers to predict surgical success and providing insights into the mechanisms of pain relief.

This review article summarized the design, synthesis, and application of innovative delivery systems for berberine, highlighting their potential to enhance wound healing through improved bioactivity and bioavailability, particularly in challenging conditions like diabetic and infected wounds.

This study suggests that human placenta hydrolysate reduces CFA-induced inflammatory pain in mice by inhibiting pro-inflammatory cytokines and protecting peripheral nerves.

This study suggests that T-cell recruitment, thrombosis, and increased vascular permeability may contribute to various symptom clusters in post-acute sequelae of COVID-19 through shared cytokine elevation.

In this study, Trapa bispinosa Roxb. pericarp extract demonstrated inhibitory effects on 5α-reductase activity both in vitro using LNCaP cells and in vivo in a mouse model of benign prostatic hyperplasia, suggesting its potential role in managing the condition.

This review discusses the role of mineral nutrients in human health, emphasizing the importance of dietary sources and education to prevent mineral deficiencies, and reports no new clinical results.

This study found that ISX9 may activate the Wnt/β-catenin signaling pathway and holds potential as a therapeutic agent for treating alopecia.

This review indicates promising potential for cinnamon supplementation to improve metabolic outcomes in PCOS, but more clinical trials with higher doses and longer durations are needed to confirm these effects.

This review examines the phytochemical constituents and pharmacological effects of licorice, discussing its potential health benefits and side effects without reporting new clinical results.

This review discusses current clinical trials targeting Wnt signaling in gastrointestinal cancers and reports no new results; the authors highlight challenges and consider alternative strategies for cancer treatment.

This review examines the life cycle, biomarkers, and functions of hair follicle stem cells, emphasizing their role in hair loss therapy and other skin and hair disorders, but reports no new clinical results.

This review discusses psychological impacts associated with facial acne, noting that high levels of anxiety and depression among these patients are not linked to oxidative stress, and reports no new clinical results.

This study reviews the etiology and treatment of skin cancer, focusing on nanotechnology's role in addressing drug resistance and evaluating nanoparticles' potential to improve treatment outcomes, including overcoming multidrug resistance.

This study found that acid regulation of the TRPV3 channel can inhibit its function from outside the cell while facilitating it from inside, providing insights into skin barrier and disorder mechanisms related to tissue acidosis.

This review discusses the complex relationship between anabolic substances and colorectal cancer risk, reporting ambiguous findings on their carcinogenic properties, potential synergy with risk factors, and protective roles.

This review discusses the use of yoga and herbal remedies for managing PCOS, reporting improved symptoms, hormonal balance, and quality of life, but presents no new clinical results.

This scoping review evaluates the connection between hypoxia and declining sex hormonal signaling in middle-aged individuals, proposing a "middle-aging hypovascularity hypoxia hypothesis" as a potential mechanism influencing age-related diseases, with implications for developing strategies to maintain healthspan.

This study found that Paeonia lactiflora and Poria cocos extracts promoted hair regrowth in a mouse model of androgenetic alopecia, with similar effects observed to normal controls.

This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.

In this study, pregnenolone was found to dose-dependently reduce L-DOPA-induced dyskinesias in a rat model of Parkinson's disease, suggesting its potential as a therapeutic target for these dyskinesias.

This review examines the potential of Cucurbitaceae seeds, such as those from watermelon, melon, and pumpkin, as sustainable and innovative ingredients in cosmetics, highlighting their rich bioactive composition and benefits for skin and hair, despite challenges like environmental instability and low permeability.

In this literature review, researchers identified 68 African plants used in hair treatment, noting that 58 of these may also help with glucose metabolism issues, suggesting a nutritional therapy approach might explain their benefits.

This review systematically summarizes the chemical components and pharmacological research on Fructus Malvae, aiming to enhance its development and application in traditional Chinese medicine; it reports no new clinical results.

This review synthesizes recent research on how Wnt signaling regulates skin, hair follicle, and nail regeneration, highlighting its compartment-specific roles and discussing targeted strategies for treating conditions like alopecia, chronic wounds, and skin cancer.

This study found that adequate vitamin D status is necessary for metformin to effectively reduce prolactin levels in men with iatrogenic hyperprolactinemia, while improvements in glycemic control were observed across all vitamin D groups.

This review reports that biomaterial-based drug delivery systems show promise in overcoming the limitations of traditional therapies for pathological scars by integrating sustained drug release with minimally invasive transdermal technologies, potentially enhancing treatment efficacy for these challenging skin lesions.

This study highlights the clinical potential of microneedles as an innovative transdermal drug delivery system for treating various skin diseases with minimal pain and high patient compliance.