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Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.

Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.

Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.

Some plant extracts may treat livestock diseases, certain animal treatments are safe and effective, but more research on drug safety and resistance is needed.

Hair follicles help attract immune cells to the skin during stress.

Skin fat helps with body temperature control and has other active roles in health.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Doctors should use a detailed patient history and physical exam to diagnose joint pain, and consult a rheumatologist early for suspected autoimmune diseases.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

The dog had sebaceous adenitis, treated with ciclosporin, leading to some hair regrowth.

Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.

Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

A mouse gene mutation increases the risk of skin cancer.

Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.

Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

Acyzol could help treat conditions caused by zinc deficiency.

Early treatment of EPDS can improve outcomes and reduce recurrence risk.