research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
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research Bioinformatic Analysis of Gene Expression Data Reveals Src Family Protein Tyrosine Kinases as Key Players in Androgenetic Alopecia
Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.
research Skin Organoids: A New Human Model for Developmental and Translational Research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research 'Omics' Approaches for Studying the Microbiome in Alopecia Areata
Omics techniques are needed to understand the scalp microbiome's role in alopecia areata for new treatments.
research Development of PEGylated Liposomes
PEGylated liposomal doxorubicin improves cancer treatment effectiveness and reduces side effects like heart damage and hair loss.
research Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome
The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
research Spatiotemporal Control of CRISPR/Cas9 Gene Editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research Skin Diseases in Pregnancy
Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.
research Autoimmune Gastritis and Parietal Cell Reactivity in Two Children with Abnormal Intestinal Permeability
Children with autoimmune gastritis showed improved intestinal health over time and should be checked for other autoimmune conditions.
research Eph Receptors and Ephrins: Therapeutic Opportunities
Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
research The Function of Zinc in Animal, Plant, and Human Nutrition
Zinc is important for growth and health in animals, plants, and humans, and not having enough can cause various problems.
research Melatonin Receptors and Their Role in Human Diseases
Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
research Stem Cells Tightly Regulate Dead Cell Clearance to Maintain Tissue Fitness
Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
research Importance of Zinc in Plant Nutrition: A Review
Zinc is essential for plant growth and human health.
research Hashimoto Thyroiditis - A Comprehensive Review
Hashimoto thyroiditis is an autoimmune disease that can lead to an underactive thyroid and is treated with medication and sometimes diet changes or surgery.
research WNT10B (Wingless-Type MMTV Integration Site Family): Role in Biological Processes and Diseases
WNT10B is linked to cancer development and affects survival and disease progression in various cancers.
research Acknowledging the Clinical Heterogeneity of Lupus Erythematosus
Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.
research Androgenic Disorders: Comprehensive Coverage of Syndromes in Women
The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.
research Replicative Stress, Stem Cells, and Aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research Dietary Fat- and Obesity-Sensitive Dermal Adipocyte PKCβ Induction and Inflammation Cross-Talk
Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.
research Developing Stratified Epithelia: Lessons from the Epidermis and Thymus
The skin and thymus develop similarly to protect and support immunity.
research Structure and Function of the Skin
The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
research Targeting Pathogenic MICA-NKG2D Interactions by Statins: A Novel Adjunct Treatment Strategy for Alopecia Areata Management?
Statins may help treat alopecia areata by reducing harmful immune interactions.
research Geriatric Dermatology: Overview
Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.
research Alopecia Areata: Overview and Insights from January 2018
Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
research Probing the Effects of Stress Mediators on the Human Hair Follicle
Stress-related substance P may lead to hair loss and negatively affect hair growth.
research Stem Cell Heterogeneity and Plasticity in Epithelia
Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
research The Circadian Clock in Skin
The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.